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An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis as compared with routine weekly treatment.
Sakuraba A, Motoya S, Watanabe K, Nishishita M, Kanke K, Matsui T, Suzuki Y, Oshima T, Kunisaki R, Matsumoto T, Hanai H, Fukunaga K, Yoshimura N, Chiba T, Funakoshi S, Aoyama N, Andoh A, Nakase H, Mizuta Y, Suzuki R, Akamatsu T, Iizuka M, Ashida T, Hibi T. Sakuraba A, et al. Among authors: kanke k. Am J Gastroenterol. 2009 Dec;104(12):2990-5. doi: 10.1038/ajg.2009.453. Epub 2009 Sep 1. Am J Gastroenterol. 2009. PMID: 19724269 Clinical Trial.
AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study.
Matsuoka K, Watanabe M, Ohmori T, Nakajima K, Ishida T, Ishiguro Y, Kanke K, Kobayashi K, Hirai F, Watanabe K, Mizusawa H, Kishida S, Miura Y, Ohta A, Kajioka T, Hibi T; AJM300 Study Group. Matsuoka K, et al. Among authors: kanke k. Lancet Gastroenterol Hepatol. 2022 Jul;7(7):648-657. doi: 10.1016/S2468-1253(22)00022-X. Epub 2022 Mar 30. Lancet Gastroenterol Hepatol. 2022. PMID: 35366419 Clinical Trial.
Once-Daily Oral Ozanimod for Japanese Patients With Ulcerative Colitis: Results From the Phase 2/3 J-True North Study.
Nakase H, Fujii T, Hisamatsu T, Suzuki Y, Watanabe M, Takahashi S, Ooi M, Takeuchi K, Kimura T, Furuya K, Aoyama N, Hasatani K, Horiki N, Kanke K, Tokito S, Sai S, Uchikawa Y, Goto S, Fujimoto G, Zhang C, Petersen A, Hibi T. Nakase H, et al. Among authors: kanke k. Gastro Hep Adv. 2025 Sep 16;5(1):100812. doi: 10.1016/j.gastha.2025.100812. eCollection 2026. Gastro Hep Adv. 2025. PMID: 41281463 Free PMC article.
44 results