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Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents.
Aldawsari FS, Aguayo-Ortiz R, Kapilashrami K, Yoo J, Luo M, Medina-Franco JL, Velázquez-Martínez CA. Aldawsari FS, et al. Among authors: kapilashrami k. J Enzyme Inhib Med Chem. 2016 Oct;31(5):695-703. doi: 10.3109/14756366.2015.1058256. Epub 2015 Jun 29. J Enzyme Inhib Med Chem. 2016. PMID: 26118420 Free PMC article.
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J, Zhang T, Meiler E, Rees M, Somersan-Karakaya S, Porras-De Francisco E, Martinez-Hoyos M, Burns-Huang K, Roberts J, Ling Y, Rhee KY, Mendoza-Losana A, Luo M, Nathan CF. Warrier T, et al. Among authors: kapilashrami k. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4523-30. doi: 10.1073/pnas.1606590113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432954 Free PMC article.
Inhibition of ALK2 with bicyclic pyridyllactams.
Witten MR, Wu L, Lai CT, Kapilashrami K, Pusey M, Gallagher K, Chen Y, Yao W. Witten MR, et al. Among authors: kapilashrami k. Bioorg Med Chem Lett. 2022 Jan 1;55:128452. doi: 10.1016/j.bmcl.2021.128452. Epub 2021 Nov 13. Bioorg Med Chem Lett. 2022. PMID: 34780900
Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2.
Nguyen MH, Atasoylu O, Wu L, Kapilashrami K, Pusey M, Gallagher K, Lai CT, Zhao P, Barbosa J, Liu K, He C, Zhang C, Styduhar ED, Witten MR, Chen Y, Lin L, Yang YO, Covington M, Diamond S, Yeleswaram S, Yao W. Nguyen MH, et al. Among authors: kapilashrami k. ACS Med Chem Lett. 2022 Jun 22;13(7):1159-1164. doi: 10.1021/acsmedchemlett.2c00206. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859885 Free PMC article.
15 results