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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.
Feldman RM, Correll CC, Kaplan KB, Deshaies RJ. Feldman RM, et al. Among authors: kaplan kb. Cell. 1997 Oct 17;91(2):221-30. doi: 10.1016/s0092-8674(00)80404-3. Cell. 1997. PMID: 9346239
APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice.
Caldwell CM, Green RA, Kaplan KB. Caldwell CM, et al. Among authors: kaplan kb. J Cell Biol. 2007 Sep 24;178(7):1109-20. doi: 10.1083/jcb.200703186. J Cell Biol. 2007. PMID: 17893240 Free PMC article.
A prescription for 'stress'--the role of Hsp90 in genome stability and cellular adaptation.
Kaplan KB, Li R. Kaplan KB, et al. Trends Cell Biol. 2012 Nov;22(11):576-83. doi: 10.1016/j.tcb.2012.08.006. Epub 2012 Sep 4. Trends Cell Biol. 2012. PMID: 22959309 Free PMC article. Review.
Chromosome passenger complexes control anaphase duration and spindle elongation via a kinesin-5 brake.
Rozelle DK, Hansen SD, Kaplan KB. Rozelle DK, et al. Among authors: kaplan kb. J Cell Biol. 2011 Apr 18;193(2):285-94. doi: 10.1083/jcb.201011002. Epub 2011 Apr 11. J Cell Biol. 2011. PMID: 21482719 Free PMC article.
Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites.
Davies AE, Kaplan KB. Davies AE, et al. Among authors: kaplan kb. J Cell Biol. 2010 Apr 19;189(2):261-74. doi: 10.1083/jcb.200910036. J Cell Biol. 2010. PMID: 20404110 Free PMC article.
A Bir1p Sli15p kinetochore passenger complex regulates septin organization during anaphase.
Thomas S, Kaplan KB. Thomas S, et al. Among authors: kaplan kb. Mol Biol Cell. 2007 Oct;18(10):3820-34. doi: 10.1091/mbc.e07-03-0201. Epub 2007 Jul 25. Mol Biol Cell. 2007. PMID: 17652458 Free PMC article.
Sgt1p is a unique co-chaperone that acts as a client adaptor to link Hsp90 to Skp1p.
Catlett MG, Kaplan KB. Catlett MG, et al. Among authors: kaplan kb. J Biol Chem. 2006 Nov 3;281(44):33739-48. doi: 10.1074/jbc.M603847200. Epub 2006 Aug 31. J Biol Chem. 2006. PMID: 16945921 Free article.
A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis.
Gillis AN, Thomas S, Hansen SD, Kaplan KB. Gillis AN, et al. Among authors: kaplan kb. J Cell Biol. 2005 Dec 5;171(5):773-84. doi: 10.1083/jcb.200507017. J Cell Biol. 2005. PMID: 16330709 Free PMC article.
APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment.
Green RA, Wollman R, Kaplan KB. Green RA, et al. Among authors: kaplan kb. Mol Biol Cell. 2005 Oct;16(10):4609-22. doi: 10.1091/mbc.e05-03-0259. Epub 2005 Jul 19. Mol Biol Cell. 2005. PMID: 16030254 Free PMC article.
The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly.
Lingelbach LB, Kaplan KB. Lingelbach LB, et al. Among authors: kaplan kb. Mol Cell Biol. 2004 Oct;24(20):8938-50. doi: 10.1128/MCB.24.20.8938-8950.2004. Mol Cell Biol. 2004. PMID: 15456868 Free PMC article.
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