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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis.
Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Kapoor M, et al. Nat Rev Rheumatol. 2011 Jan;7(1):33-42. doi: 10.1038/nrrheum.2010.196. Epub 2010 Nov 30. Nat Rev Rheumatol. 2011. PMID: 21119608 Review.
Autophagy: controlling cell fate in rheumatic diseases.
Rockel JS, Kapoor M. Rockel JS, et al. Among authors: kapoor m. Nat Rev Rheumatol. 2016 Sep;12(9):517-31. doi: 10.1038/nrrheum.2016.92. Epub 2016 Jun 23. Nat Rev Rheumatol. 2016. PMID: 27334205 Review.
mTOR: a potential therapeutic target in osteoarthritis?
Pal B, Endisha H, Zhang Y, Kapoor M. Pal B, et al. Among authors: kapoor m. Drugs R D. 2015 Mar;15(1):27-36. doi: 10.1007/s40268-015-0082-z. Drugs R D. 2015. PMID: 25688060 Free PMC article. Review.
Fibrosis--a lethal component of systemic sclerosis.
Ho YY, Lagares D, Tager AM, Kapoor M. Ho YY, et al. Among authors: kapoor m. Nat Rev Rheumatol. 2014 Jul;10(7):390-402. doi: 10.1038/nrrheum.2014.53. Epub 2014 Apr 22. Nat Rev Rheumatol. 2014. PMID: 24752182 Review.
Cellular Aging, Senescence and Autophagy Processes in Osteoarthritis.
Benderdour M, Martel-Pelletier J, Pelletier JP, Kapoor M, Zunzunegui MV, Fahmi H. Benderdour M, et al. Among authors: kapoor m. Curr Aging Sci. 2015;8(2):147-57. doi: 10.2174/1874609808666150727111530. Curr Aging Sci. 2015. PMID: 26212056 Review.
The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.
Valverde-Franco G, Hum D, Matsuo K, Lussier B, Pelletier JP, Fahmi H, Kapoor M, Martel-Pelletier J. Valverde-Franco G, et al. Among authors: kapoor m. Am J Pathol. 2015 Feb;185(2):335-46. doi: 10.1016/j.ajpath.2014.10.004. Epub 2014 Nov 29. Am J Pathol. 2015. PMID: 25453723
PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.
Vasheghani F, Zhang Y, Li YH, Blati M, Fahmi H, Lussier B, Roughley P, Lagares D, Endisha H, Saffar B, Lajeunesse D, Marshall WK, Rampersaud YR, Mahomed NN, Gandhi R, Pelletier JP, Martel-Pelletier J, Kapoor M. Vasheghani F, et al. Among authors: kapoor m. Ann Rheum Dis. 2015 Mar;74(3):569-78. doi: 10.1136/annrheumdis-2014-205743. Epub 2015 Jan 8. Ann Rheum Dis. 2015. PMID: 25573665 Free PMC article.
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.
Valverde-Franco G, Pelletier JP, Fahmi H, Hum D, Matsuo K, Lussier B, Kapoor M, Martel-Pelletier J. Valverde-Franco G, et al. Among authors: kapoor m. Arthritis Rheum. 2012 Nov;64(11):3614-25. doi: 10.1002/art.34638. Arthritis Rheum. 2012. PMID: 22833446
Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model.
Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M. Monemdjou R, et al. Among authors: kapoor m. Arthritis Rheum. 2012 May;64(5):1551-61. doi: 10.1002/art.33490. Arthritis Rheum. 2012. PMID: 22131019 Free PMC article.
Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes.
Nebbaki SS, El Mansouri FE, Afif H, Kapoor M, Benderdour M, Duval N, Pelletier JP, Martel-Pelletier J, Fahmi H. Nebbaki SS, et al. Among authors: kapoor m. Arthritis Res Ther. 2012 Mar 28;14(2):R69. doi: 10.1186/ar3788. Arthritis Res Ther. 2012. PMID: 22455954 Free PMC article.
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