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PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.
Vasheghani F, Zhang Y, Li YH, Blati M, Fahmi H, Lussier B, Roughley P, Lagares D, Endisha H, Saffar B, Lajeunesse D, Marshall WK, Rampersaud YR, Mahomed NN, Gandhi R, Pelletier JP, Martel-Pelletier J, Kapoor M. Vasheghani F, et al. Among authors: kapoor m. Ann Rheum Dis. 2015 Mar;74(3):569-78. doi: 10.1136/annrheumdis-2014-205743. Epub 2015 Jan 8. Ann Rheum Dis. 2015. PMID: 25573665 Free PMC article.
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.
McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M. McCann MR, et al. Among authors: kapoor m. Arthritis Res Ther. 2011;13(1):R6. doi: 10.1186/ar3226. Epub 2011 Jan 25. Arthritis Res Ther. 2011. PMID: 21266028 Free PMC article.
Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model.
Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M. Monemdjou R, et al. Among authors: kapoor m. Arthritis Rheum. 2012 May;64(5):1551-61. doi: 10.1002/art.33490. Arthritis Rheum. 2012. PMID: 22131019 Free PMC article.
779 results