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A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.
Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, Mikaelyan A, Roberts LR, Demetris AJ, Sun Z, Nevens F, Roskams T, Thorgeirsson SS. Lee JS, et al. Nat Med. 2006 Apr;12(4):410-6. doi: 10.1038/nm1377. Epub 2006 Mar 12. Nat Med. 2006. PMID: 16532004
Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice.
Factor VM, Seo D, Ishikawa T, Kaposi-Novak P, Marquardt JU, Andersen JB, Conner EA, Thorgeirsson SS. Factor VM, et al. Among authors: kaposi novak p. PLoS One. 2010 Sep 16;5(9):e12739. doi: 10.1371/journal.pone.0012739. PLoS One. 2010. PMID: 20862286 Free PMC article.
Central role of c-Myc during malignant conversion in human hepatocarcinogenesis.
Kaposi-Novak P, Libbrecht L, Woo HG, Lee YH, Sears NC, Coulouarn C, Conner EA, Factor VM, Roskams T, Thorgeirsson SS. Kaposi-Novak P, et al. Cancer Res. 2009 Apr 1;69(7):2775-82. doi: 10.1158/0008-5472.CAN-08-3357. Epub 2009 Mar 10. Cancer Res. 2009. PMID: 19276364 Free PMC article.
Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
Coulouarn C, Gomez-Quiroz LE, Lee JS, Kaposi-Novak P, Conner EA, Goldina TA, Onishchenko GE, Factor VM, Thorgeirsson SS. Coulouarn C, et al. Hepatology. 2006 Oct;44(4):1003-11. doi: 10.1002/hep.21293. Hepatology. 2006. PMID: 17006931
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype.
Kaposi-Novak P, Lee JS, Gòmez-Quiroz L, Coulouarn C, Factor VM, Thorgeirsson SS. Kaposi-Novak P, et al. J Clin Invest. 2006 Jun;116(6):1582-95. doi: 10.1172/JCI27236. Epub 2006 May 18. J Clin Invest. 2006. PMID: 16710476 Free PMC article.
Loss of c-Met accelerates development of liver fibrosis in response to CCl(4) exposure through deregulation of multiple molecular pathways.
Marquardt JU, Seo D, Gómez-Quiroz LE, Uchida K, Gillen MC, Kitade M, Kaposi-Novak P, Conner EA, Factor VM, Thorgeirsson SS. Marquardt JU, et al. Among authors: kaposi novak p. Biochim Biophys Acta. 2012 Jun;1822(6):942-51. doi: 10.1016/j.bbadis.2012.02.012. Epub 2012 Feb 22. Biochim Biophys Acta. 2012. PMID: 22386877 Free PMC article.
Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis.
Takami T, Kaposi-Novak P, Uchida K, Gomez-Quiroz LE, Conner EA, Factor VM, Thorgeirsson SS. Takami T, et al. Among authors: kaposi novak p. Cancer Res. 2007 Oct 15;67(20):9844-51. doi: 10.1158/0008-5472.CAN-07-1905. Cancer Res. 2007. PMID: 17942915 Free article.
Hepatocyte-specific c-Met deletion disrupts redox homeostasis and sensitizes to Fas-mediated apoptosis.
Gómez-Quiroz LE, Factor VM, Kaposi-Novak P, Coulouarn C, Conner EA, Thorgeirsson SS. Gómez-Quiroz LE, et al. Among authors: kaposi novak p. J Biol Chem. 2008 May 23;283(21):14581-9. doi: 10.1074/jbc.M707733200. Epub 2008 Mar 18. J Biol Chem. 2008. PMID: 18348981 Free PMC article.
[Comparative genomic classification of human hepatocellular carcinoma].
Kaposi-Novák P. Kaposi-Novák P. Magy Onkol. 2009 Mar;53(1):61-7. doi: 10.1556/MOnkol.53.2009.1.9. Magy Onkol. 2009. PMID: 19318328 Free article. Hungarian.
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