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Discovery of quinoline-based irreversible BTK inhibitors.
de Bruin G, Demont D, de Zwart E, Verkaik S, Hoogenboom N, van de Kar B, van Lith B, Emmelot-van Hoek M, Gulrajani M, Covey T, Kaptein A, Barf T. de Bruin G, et al. Among authors: kaptein a. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127261. doi: 10.1016/j.bmcl.2020.127261. Epub 2020 May 13. Bioorg Med Chem Lett. 2020. PMID: 32527559
Writing cancer.
Kaptein AA. Kaptein AA. Support Care Cancer. 2021 Aug;29(8):4375-4380. doi: 10.1007/s00520-020-05920-0. Epub 2021 Jan 8. Support Care Cancer. 2021. PMID: 33420530 Review.
Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013-14) trial.
Lugtenberg RT, de Groot S, Kaptein AA, Fischer MJ, Kranenbarg EM, Carpentier MD, Cohen D, de Graaf H, Heijns JB, Portielje JEA, van de Wouw AJ, Imholz ALT, Kessels LW, Vrijaldenhoven S, Baars A, Fiocco M, van der Hoeven JJM, Gelderblom H, Longo VD, Pijl H, Kroep JR; Dutch Breast Cancer Research Group (BOOG). Lugtenberg RT, et al. Among authors: kaptein aa. Breast Cancer Res Treat. 2021 Feb;185(3):741-758. doi: 10.1007/s10549-020-05991-x. Epub 2020 Nov 11. Breast Cancer Res Treat. 2021. PMID: 33179154 Free PMC article. Clinical Trial.
Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis.
van der Wel T, Hilhorst R, den Dulk H, van den Hooven T, Prins NM, Wijnakker JAPM, Florea BI, Lenselink EB, van Westen GJP, Ruijtenbeek R, Overkleeft HS, Kaptein A, Barf T, van der Stelt M. van der Wel T, et al. Among authors: kaptein a. Nat Commun. 2020 Jun 25;11(1):3216. doi: 10.1038/s41467-020-17027-5. Nat Commun. 2020. PMID: 32587248 Free PMC article.
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