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Page 1
The RAF proteins take centre stage.
Wellbrock C, Karasarides M, Marais R. Wellbrock C, et al. Among authors: karasarides m. Nat Rev Mol Cell Biol. 2004 Nov;5(11):875-85. doi: 10.1038/nrm1498. Nat Rev Mol Cell Biol. 2004. PMID: 15520807 Review.
V599EB-RAF is an oncogene in melanocytes.
Wellbrock C, Ogilvie L, Hedley D, Karasarides M, Martin J, Niculescu-Duvaz D, Springer CJ, Marais R. Wellbrock C, et al. Among authors: karasarides m. Cancer Res. 2004 Apr 1;64(7):2338-42. doi: 10.1158/0008-5472.can-03-3433. Cancer Res. 2004. PMID: 15059882 Free article.
B-RAF is a therapeutic target in melanoma.
Karasarides M, Chiloeches A, Hayward R, Niculescu-Duvaz D, Scanlon I, Friedlos F, Ogilvie L, Hedley D, Martin J, Marshall CJ, Springer CJ, Marais R. Karasarides M, et al. Oncogene. 2004 Aug 19;23(37):6292-8. doi: 10.1038/sj.onc.1207785. Oncogene. 2004. PMID: 15208680
JNK2 is a positive regulator of the cJun transcription factor.
Jaeschke A, Karasarides M, Ventura JJ, Ehrhardt A, Zhang C, Flavell RA, Shokat KM, Davis RJ. Jaeschke A, et al. Among authors: karasarides m. Mol Cell. 2006 Sep 15;23(6):899-911. doi: 10.1016/j.molcel.2006.07.028. Mol Cell. 2006. PMID: 16973441 Free article.
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.
Hübner A, Mulholland DJ, Standen CL, Karasarides M, Cavanagh-Kyros J, Barrett T, Chi H, Greiner DL, Tournier C, Sawyers CL, Flavell RA, Wu H, Davis RJ. Hübner A, et al. Among authors: karasarides m. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12046-51. doi: 10.1073/pnas.1209660109. Epub 2012 Jul 2. Proc Natl Acad Sci U S A. 2012. PMID: 22753496 Free PMC article.