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Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands.
Encell LP, Friedman Ohana R, Zimmerman K, Otto P, Vidugiris G, Wood MG, Los GV, McDougall MG, Zimprich C, Karassina N, Learish RD, Hurst R, Hartnett J, Wheeler S, Stecha P, English J, Zhao K, Mendez J, Benink HA, Murphy N, Daniels DL, Slater MR, Urh M, Darzins A, Klaubert DH, Bulleit RF, Wood KV. Encell LP, et al. Among authors: karassina n. Curr Chem Genomics. 2012;6:55-71. doi: 10.2174/1875397301206010055. Epub 2012 Oct 5. Curr Chem Genomics. 2012. PMID: 23248739 Free PMC article.
HaloTag: a novel protein labeling technology for cell imaging and protein analysis.
Los GV, Encell LP, McDougall MG, Hartzell DD, Karassina N, Zimprich C, Wood MG, Learish R, Ohana RF, Urh M, Simpson D, Mendez J, Zimmerman K, Otto P, Vidugiris G, Zhu J, Darzins A, Klaubert DH, Bulleit RF, Wood KV. Los GV, et al. Among authors: karassina n. ACS Chem Biol. 2008 Jun 20;3(6):373-82. doi: 10.1021/cb800025k. ACS Chem Biol. 2008. PMID: 18533659
A bioluminescent assay for measuring glucose uptake.
Valley MP, Karassina N, Aoyama N, Carlson C, Cali JJ, Vidugiriene J. Valley MP, et al. Among authors: karassina n. Anal Biochem. 2016 Jul 15;505:43-50. doi: 10.1016/j.ab.2016.04.010. Epub 2016 Apr 26. Anal Biochem. 2016. PMID: 27130501
Cytotoxicity Assays: In Vitro Methods to Measure Dead Cells.
Riss T, Niles A, Moravec R, Karassina N, Vidugiriene J. Riss T, et al. Among authors: karassina n. 2019 May 1. In: Markossian S, Grossman A, Arkin M, Auld D, Austin C, Baell J, Brimacombe K, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Lal-Nag M, Li Z, Manro JR, McGee J, McManus O, Pearson M, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. 2019 May 1. In: Markossian S, Grossman A, Arkin M, Auld D, Austin C, Baell J, Brimacombe K, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Lal-Nag M, Li Z, Manro JR, McGee J, McManus O, Pearson M, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. PMID: 31070879 Free Books & Documents. Review.
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