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Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation.
Zhou Y, Bastian IN, Long MD, Dow M, Li W, Liu T, Ngu RK, Antonucci L, Huang JY, Phung QT, Zhao XH, Banerjee S, Lin XJ, Wang H, Dang B, Choi S, Karin D, Su H, Ellisman MH, Jamieson C, Bosenberg M, Cheng Z, Haybaeck J, Kenner L, Fisch KM, Bourgon R, Hernandez G, Lill JR, Liu S, Carter H, Mellman I, Karin M, Shalapour S. Zhou Y, et al. Among authors: karin d. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2025840118. doi: 10.1073/pnas.2025840118. Proc Natl Acad Sci U S A. 2021. PMID: 33602823 Free PMC article.
NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, Ganguly S, Lan T, Karin M, Kisseleva T, Brenner DA. Liang S, et al. Among authors: karin d. Gastroenterology. 2019 Mar;156(4):1156-1172.e6. doi: 10.1053/j.gastro.2018.11.019. Epub 2018 Nov 13. Gastroenterology. 2019. PMID: 30445007 Free PMC article.
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.
Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, Zhao P, Brodt P, Mckillop IH, Quehenberger O, Dennis E, Saltiel A, Tsukamoto H, Gao B, Karin M, Brenner DA, Kisseleva T. Ma HY, et al. Among authors: karin d. J Hepatol. 2020 May;72(5):946-959. doi: 10.1016/j.jhep.2019.12.016. Epub 2019 Dec 31. J Hepatol. 2020. PMID: 31899206 Free PMC article.
18F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models.
Le TM, Lee HR, Abt ER, Rashid K, Creech AL, Liang K, Cui J, Cho A, Wei L, Labora A, Chan C, Sanchez E, Kriti K, Karin D, Li L, Wu N, Mona C, Carlucci G, Hugo W, Wu TT, Donahue TR, Czernin J, Radu CG. Le TM, et al. Among authors: karin d. J Nucl Med. 2023 Jan;64(1):117-123. doi: 10.2967/jnumed.122.264121. Epub 2022 Jun 23. J Nucl Med. 2023. PMID: 35738905 Free PMC article.
Correction: ERK mediates interferon gamma-induced melanoma cell death.
Champhekar A, Heymans R, Saco J, Font GT, Gonzalez C, Gao A, Pham J, Lee J, Maryoung R, Medina E, Campbell KM, Karin D, Austin D, Damioseaux R, Ribas A. Champhekar A, et al. Among authors: karin d. Mol Cancer. 2024 Feb 5;23(1):29. doi: 10.1186/s12943-024-01949-5. Mol Cancer. 2024. PMID: 38317137 Free PMC article. No abstract available.
ERK mediates interferon gamma-induced melanoma cell death.
Champhekar A, Heymans R, Saco J, Turon Font G, Gonzalez C, Gao A, Pham J, Lee J, Maryoung R, Medina E, Campbell KM, Karin D, Austin D, Damioseaux R, Ribas A. Champhekar A, et al. Among authors: karin d. Mol Cancer. 2023 Oct 6;22(1):165. doi: 10.1186/s12943-023-01868-x. Mol Cancer. 2023. PMID: 37803324 Free PMC article.
Remodeling of the tumor microenvironment through PAK4 inhibition sensitizes tumors to immune checkpoint blockade.
Abril-Rodríguez G, Torrejon DY, Karin D, Campbell KM, Medina E, Saco JD, Galvez M, Champhekar AS, Perez-Garcilazo I, Baselga-Carretero I, Singh J, Comin-Anduix B, Puig-Saus C, Ribas A. Abril-Rodríguez G, et al. Among authors: karin d. Cancer Res Commun. 2022 Oct;2(10):1214-1228. doi: 10.1158/2767-9764.crc-21-0133. Epub 2022 Oct 19. Cancer Res Commun. 2022. PMID: 36588582 Free PMC article.
11 results