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Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.
Marin M, Karis A, Visser P, Grosveld F, Philipsen S. Marin M, et al. Among authors: karis a. Cell. 1997 May 16;89(4):619-28. doi: 10.1016/s0092-8674(00)80243-3. Cell. 1997. PMID: 9160753
A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse.
Lindeboom F, Gillemans N, Karis A, Jaegle M, Meijer D, Grosveld F, Philipsen S. Lindeboom F, et al. Among authors: karis a. Nucleic Acids Res. 2003 Sep 15;31(18):5405-12. doi: 10.1093/nar/gkg723. Nucleic Acids Res. 2003. PMID: 12954777 Free PMC article.
Hearing loss following Gata3 haploinsufficiency is caused by cochlear disorder.
van der Wees J, van Looij MA, de Ruiter MM, Elias H, van der Burg H, Liem SS, Kurek D, Engel JD, Karis A, van Zanten BG, de Zeeuw CI, Grosveld FG, van Doorninck JH. van der Wees J, et al. Among authors: karis a. Neurobiol Dis. 2004 Jun;16(1):169-78. doi: 10.1016/j.nbd.2004.02.004. Neurobiol Dis. 2004. PMID: 15207274
Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo.
Nawijn MC, Dingjan GM, Ferreira R, Lambrecht BN, Karis A, Grosveld F, Savelkoul H, Hendriks RW. Nawijn MC, et al. Among authors: karis a. J Immunol. 2001 Jul 15;167(2):724-32. doi: 10.4049/jimmunol.167.2.724. J Immunol. 2001. PMID: 11441076
Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice.
Nawijn MC, Ferreira R, Dingjan GM, Kahre O, Drabek D, Karis A, Grosveld F, Hendriks RW. Nawijn MC, et al. Among authors: karis a. J Immunol. 2001 Jul 15;167(2):715-23. doi: 10.4049/jimmunol.167.2.715. J Immunol. 2001. PMID: 11441075
Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus.
Hendriks RW, Nawijn MC, Engel JD, van Doorninck H, Grosveld F, Karis A. Hendriks RW, et al. Among authors: karis a. Eur J Immunol. 1999 Jun;29(6):1912-8. doi: 10.1002/(SICI)1521-4141(199906)29:06<1912::AID-IMMU1912>3.0.CO;2-D. Eur J Immunol. 1999. PMID: 10382753
GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei.
van Doorninck JH, van Der Wees J, Karis A, Goedknegt E, Engel JD, Coesmans M, Rutteman M, Grosveld F, De Zeeuw CI. van Doorninck JH, et al. Among authors: karis a. J Neurosci. 1999 Jun 15;19(12):RC12. doi: 10.1523/JNEUROSCI.19-12-j0002.1999. J Neurosci. 1999. PMID: 10366650 Free PMC article.
The POU factor Oct-6 and Schwann cell differentiation.
Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D. Jaegle M, et al. Among authors: karis a. Science. 1996 Jul 26;273(5274):507-10. doi: 10.1126/science.273.5274.507. Science. 1996. PMID: 8662541
The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery.
Whyatt DJ, Karis A, Harkes IC, Verkerk A, Gillemans N, Elefanty AG, Vairo G, Ploemacher R, Grosveld F, Philipsen S. Whyatt DJ, et al. Among authors: karis a. Genes Funct. 1997 Feb;1(1):11-24. doi: 10.1046/j.1365-4624.1997.00003.x. Genes Funct. 1997. PMID: 9680325
Transcription factor Sp3 is essential for post-natal survival and late tooth development.
Bouwman P, Göllner H, Elsässer HP, Eckhoff G, Karis A, Grosveld F, Philipsen S, Suske G. Bouwman P, et al. Among authors: karis a. EMBO J. 2000 Feb 15;19(4):655-61. doi: 10.1093/emboj/19.4.655. EMBO J. 2000. PMID: 10675334 Free PMC article.
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