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Epidemiologic estimate of the proportion of fatalities related to occupational factors in Finland.
Nurminen M, Karjalainen A. Nurminen M, et al. Among authors: karjalainen a. Scand J Work Environ Health. 2001 Jun;27(3):161-213. doi: 10.5271/sjweh.605. Scand J Work Environ Health. 2001. PMID: 11444413
A Finnish job-exposure matrix supplied data on the prevalence of exposure for specific agents and the level of exposure among exposed workers. ...
A Finnish job-exposure matrix supplied data on the prevalence of exposure for specific agents and the level of exposure among exposed
Combined effect of polymorphic GST genes on individual susceptibility to lung cancer.
Saarikoski ST, Voho A, Reinikainen M, Anttila S, Karjalainen A, Malaveille C, Vainio H, Husgafvel-Pursiainen K, Hirvonen A. Saarikoski ST, et al. Among authors: karjalainen a. Int J Cancer. 1998 Aug 12;77(4):516-21. doi: 10.1002/(sici)1097-0215(19980812)77:4<516::aid-ijc7>3.0.co;2-x. Int J Cancer. 1998. PMID: 9679751
None of the genotypes studied had a statistically significant effect on lung cancer risk, when studied separately. However, a significant association was observed for concurrent lack of the GSTM1 and GSTT1 genes and susceptibility to squamous cell carcinoma. ...
None of the genotypes studied had a statistically significant effect on lung cancer risk, when studied separately. However, a
Lung cancer and past occupational exposure to asbestos. Role of p53 and K-ras mutations.
Husgafvel-Pursiainen K, Karjalainen A, Kannio A, Anttila S, Partanen T, Ojajärvi A, Vainio H. Husgafvel-Pursiainen K, et al. Among authors: karjalainen a. Am J Respir Cell Mol Biol. 1999 Apr;20(4):667-74. doi: 10.1165/ajrcmb.20.4.3404. Am J Respir Cell Mol Biol. 1999. PMID: 10100998
A pulmonary burden of >/= 1 x 10(6) asbestos fibers per gram of lung tissue, indicating work-related exposure, was found in 32% of the patients for whom fiber-analysis data were available (33 of 102 patients, all men). ...In male ever-smokers, a long duration of
A pulmonary burden of >/= 1 x 10(6) asbestos fibers per gram of lung tissue, indicating work-related exposure, was found in 32% of
Association between pleural plaques and coronary heart disease.
Korhola O, Hiltunen A, Karjalainen A, Martikainen R, Riihimäki H. Korhola O, et al. Among authors: karjalainen a. Scand J Work Environ Health. 2001 Apr;27(2):154-5. doi: 10.5271/sjweh.603. Scand J Work Environ Health. 2001. PMID: 11409599
OBJECTIVE: The aim of this study was to verify a clinical impression that patients with coronary heart disease disproportionately frequently have calcified pleural plaques. ...A generalized linear model with binomial distribution and log link was used to estimate th …
OBJECTIVE: The aim of this study was to verify a clinical impression that patients with coronary heart disease disproportionately fre …
Incidence of cancer among Finnish patients with asbestos-related pulmonary or pleural fibrosis.
Karjalainen A, Pukkala E, Kauppinen T, Partanen T. Karjalainen A, et al. Cancer Causes Control. 1999 Feb;10(1):51-7. doi: 10.1023/a:1008845332422. Cancer Causes Control. 1999. PMID: 10334642
RESULTS: Compared with the total cancer incidence in Finland, men with asbestosis had a raised risk of lung cancer (standardized incidence ratio [SIR] = 6.7; 95% confidence interval [CI] = 5.6-7.9), mesothelioma (SIR = 32, CI = 14-60) and cancer of the larynx (SIR = 4.2, C …
RESULTS: Compared with the total cancer incidence in Finland, men with asbestosis had a raised risk of lung cancer (standardized inci …
Trends in mesothelioma incidence and occupational mesotheliomas in Finland in 1960-1995.
Karjalainen A, Pukkala E, Mattson K, Tammilehto L, Vainio H. Karjalainen A, et al. Scand J Work Environ Health. 1997 Aug;23(4):266-70. doi: 10.5271/sjweh.219. Scand J Work Environ Health. 1997. PMID: 9322817
Asbestos--a continuing concern.
Karjalainen A. Karjalainen A. Scand J Work Environ Health. 1997 Apr;23(2):81-2. doi: 10.5271/sjweh.184. Scand J Work Environ Health. 1997. PMID: 9167230 No abstract available.
Cancer incidence and mortality among Finnish asbestos sprayers and in asbestosis and silicosis patients.
Oksa P, Pukkala E, Karjalainen A, Ojajärvi A, Huuskonen MS. Oksa P, et al. Among authors: karjalainen a. Am J Ind Med. 1997 Jun;31(6):693-8. doi: 10.1002/(sici)1097-0274(199706)31:6<693::aid-ajim4>3.0.co;2-s. Am J Ind Med. 1997. PMID: 9131223
It was concluded that pneumoconioses patients and asbestos-exposed workers have a markedly elevated risk for cancer. Asbestos-induced occupational cancers are not only diseases of the elderly, since the relative risk is high also for middle-aged people....
It was concluded that pneumoconioses patients and asbestos-exposed workers have a markedly elevated risk for cancer. Asbestos-induced …
Finnish Institute of Occupational Health Asbestos Program 1987-1992.
Huuskonen MS, Koskinen K, Tossavainen A, Karjalainen A, Rinne JP, Rantanen J. Huuskonen MS, et al. Among authors: karjalainen a. Am J Ind Med. 1995 Jul;28(1):123-42. doi: 10.1002/ajim.4700280111. Am J Ind Med. 1995. PMID: 7573071
In 1987-1992, the Finnish Institute of Occupational Health (FIOH) implemented a nationwide asbestos program aimed at preventing asbestos-related risks in good cooperation with governmental authorities, industry, trade unions, the health care and insurance systems, and mass …
In 1987-1992, the Finnish Institute of Occupational Health (FIOH) implemented a nationwide asbestos program aimed at preventing asbes …
CYP1A1 levels in lung tissue of tobacco smokers and polymorphisms of CYP1A1 and aromatic hydrocarbon receptor.
Anttila S, Tuominen P, Hirvonen A, Nurminen M, Karjalainen A, Hankinson O, Elovaara E. Anttila S, et al. Among authors: karjalainen a. Pharmacogenetics. 2001 Aug;11(6):501-9. doi: 10.1097/00008571-200108000-00005. Pharmacogenetics. 2001. PMID: 11505220
Induction of a polycyclic aromatic hydrocarbon-metabolizing cytochrome P450 isoform CYP1A1 is regulated by aromatic hydrocarbon receptor (AHR). High inducibility of CYP1A1, possibly due to genetic polymorphisms, has been considered to be a risk factor for lung cance …
Induction of a polycyclic aromatic hydrocarbon-metabolizing cytochrome P450 isoform CYP1A1 is regulated by aromatic hydrocarbon recep …
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