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Identification and characterization of SarH1, a new global regulator of virulence gene expression in Staphylococcus aureus.
Tegmark K, Karlsson A, Arvidson S. Tegmark K, et al. Among authors: karlsson a. Mol Microbiol. 2000 Jul;37(2):398-409. doi: 10.1046/j.1365-2958.2000.02003.x. Mol Microbiol. 2000. PMID: 10931334
One protein (29 kDa), with affinity for all four promoters, showed a high degree of similarity to SarA and was named SarH1 (Sar homologue 1). ...In conclusion, we show that both the agr-dependent suppression of protein A production and the sarA-dependent stimulation …
One protein (29 kDa), with affinity for all four promoters, showed a high degree of similarity to SarA and was named SarH1 (Sar homol …
MT-2 cell tropism as prognostic marker for disease progression in human immunodeficiency virus type 1 infection.
Karlsson A, Parsmyr K, Sandström E, Fenyö EM, Albert J. Karlsson A, et al. J Clin Microbiol. 1994 Feb;32(2):364-70. doi: 10.1128/JCM.32.2.364-370.1994. J Clin Microbiol. 1994. PMID: 7908672 Free PMC article.
A stable or slowly decreasing CD4+ lymphocyte count changed into a more rapid fall in 44% of the patients, no significant change in rate of decline could be noted in 44% of the patients, while a stable CD4+ lymphocyte level after a change in MT-2 tropi
A stable or slowly decreasing CD4+ lymphocyte count changed into a more rapid fall in 44% of the patients, no significant chan
Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyurea.
Zheng X, Johansson M, Karlsson A. Zheng X, et al. Among authors: karlsson a. Mol Pharmacol. 2001 Aug;60(2):262-6. doi: 10.1124/mol.60.2.262. Mol Pharmacol. 2001. PMID: 11455012
We used two human cancer cell lines transduced with a retrovirus encoding the Dm-dNK cDNA and investigated whether the cells expressing the enzyme can induce cell death of untransduced cells, a phenomenon known as the "bystander effect". A bystander effect wa …
We used two human cancer cell lines transduced with a retrovirus encoding the Dm-dNK cDNA and investigated whether the cells expressi …
Decreased amounts of cell wall-associated protein A and fibronectin-binding proteins in Staphylococcus aureus sarA mutants due to up-regulation of extracellular proteases.
Karlsson A, Saravia-Otten P, Tegmark K, Morfeldt E, Arvidson S. Karlsson A, et al. Infect Immun. 2001 Aug;69(8):4742-8. doi: 10.1128/IAI.69.8.4742-4748.2001. Infect Immun. 2001. PMID: 11447146 Free PMC article.
Inactivation of either ssp or aur in the prototype S. aureus strain 8325-4 resulted in a threefold increase in the amount of cell-bound FnBPs. Inactivation of the same protease genes in a sarA mutant of 8325-4 resulted in a 10- to 20-fold increase in cell-bou …
Inactivation of either ssp or aur in the prototype S. aureus strain 8325-4 resulted in a threefold increase in the amount of cell-bou …
Conserved gene structure and transcription factor sites in the human and mouse deoxycytidine kinase genes.
Johansson M, Norda A, Karlsson A. Johansson M, et al. Among authors: karlsson a. FEBS Lett. 2000 Dec 29;487(2):209-12. doi: 10.1016/s0014-5793(00)02347-4. FEBS Lett. 2000. PMID: 11150511
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.
Van Rompay AR, Norda A, Lindén K, Johansson M, Karlsson A. Van Rompay AR, et al. Among authors: karlsson a. Mol Pharmacol. 2001 May;59(5):1181-6. doi: 10.1124/mol.59.5.1181. Mol Pharmacol. 2001. PMID: 11306702
Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme.
Van Rompay AR, Johansson M, Karlsson A. Van Rompay AR, et al. Among authors: karlsson a. Mol Pharmacol. 1999 Sep;56(3):562-9. doi: 10.1124/mol.56.3.562. Mol Pharmacol. 1999. PMID: 10462544
We further showed, in a combined enzymatic assay, that human deoxycytidine kinase and UMP-CMP kinase together phosphorylated araC, dFdC, and 2',3'-dideoxycytidine to their diphosphate forms. Northern blot analysis showed that the UMP-CMP kinase mRNA was ubiquitously presen …
We further showed, in a combined enzymatic assay, that human deoxycytidine kinase and UMP-CMP kinase together phosphorylated araC, dF …
Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster.
Johansson M, van Rompay AR, Degrève B, Balzarini J, Karlsson A. Johansson M, et al. Among authors: karlsson a. J Biol Chem. 1999 Aug 20;274(34):23814-9. doi: 10.1074/jbc.274.34.23814. J Biol Chem. 1999. PMID: 10446143
The broad substrate specificity of this enzyme together with a high catalytic rate makes it unique among the nucleoside kinases. ...The cDNA cloning and characterization of Dm-dNK will be the basis for studies on the use of this multisubstrate nucleoside kinase as a
The broad substrate specificity of this enzyme together with a high catalytic rate makes it unique among the nucleoside kinases. ...T …
Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein.
Van Rompay AR, Johansson M, Karlsson A. Van Rompay AR, et al. Among authors: karlsson a. Eur J Biochem. 1999 Apr;261(2):509-17. doi: 10.1046/j.1432-1327.1999.00294.x. Eur J Biochem. 1999. PMID: 10215863
We report the cDNA cloning of a novel 22-kDa human enzyme that is sequence related to the human adenylate kinases and to UMP/CMP kinase of several species. ...When GTP was used as phosphate donor, the enzyme phosphorylated AMP, CMP, and to a small extent dCMP. Expre …
We report the cDNA cloning of a novel 22-kDa human enzyme that is sequence related to the human adenylate kinases and to UMP/CMP kina …
Cloning and expression of human deoxyguanosine kinase cDNA.
Johansson M, Karlsson A. Johansson M, et al. Among authors: karlsson a. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7258-62. doi: 10.1073/pnas.93.14.7258. Proc Natl Acad Sci U S A. 1996. PMID: 8692979 Free PMC article.
The N terminus of the deduced amino acid sequence had properties characteristic for a mitochondrial translocation signal, and cleavage at a putative mitochondrial peptidase cleavage site would give a mature protein size of 28 kDa. ...To our knowledge, this is …
The N terminus of the deduced amino acid sequence had properties characteristic for a mitochondrial translocation signal, and cleavag …
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