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The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
Hum Mol Genet. 2013 Aug 1;22(15):3048-62. doi: 10.1093/hmg/ddt162. Epub 2013 Apr 9.
Hum Mol Genet. 2013.
PMID: 23571107
Free PMC article.
FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.
Karolak MR, Yang X, Elefteriou F.
Karolak MR, et al.
Hum Mol Genet. 2015 May 1;24(9):2552-64. doi: 10.1093/hmg/ddv019. Epub 2015 Jan 23.
Hum Mol Genet. 2015.
PMID: 25616962
Free PMC article.
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Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice.
Campbell JP, Karolak MR, Ma Y, Perrien DS, Masood-Campbell SK, Penner NL, Munoz SA, Zijlstra A, Yang X, Sterling JA, Elefteriou F.
Campbell JP, et al. Among authors: karolak mr.
PLoS Biol. 2012 Jul;10(7):e1001363. doi: 10.1371/journal.pbio.1001363. Epub 2012 Jul 17.
PLoS Biol. 2012.
PMID: 22815651
Free PMC article.
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TRIzol and Alu qPCR-based quantification of metastatic seeding within the skeleton.
Preston Campbell J, Mulcrone P, Masood SK, Karolak M, Merkel A, Hebron K, Zijlstra A, Sterling J, Elefteriou F.
Preston Campbell J, et al.
Sci Rep. 2015 Aug 14;5:12635. doi: 10.1038/srep12635.
Sci Rep. 2015.
PMID: 26271202
Free PMC article.
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Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo.
Escalante AM, McGrath RT, Karolak MR, Dorr RT, Lynch RM, Landowski TH.
Escalante AM, et al. Among authors: karolak mr.
Cancer Chemother Pharmacol. 2013 Jun;71(6):1567-76. doi: 10.1007/s00280-013-2156-3. Epub 2013 Apr 10.
Cancer Chemother Pharmacol. 2013.
PMID: 23572175
Free PMC article.
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