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Lidocaine exhibits dose- and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro.
Karpie JC, Chu CR. Karpie JC, et al. Am J Sports Med. 2007 Oct;35(10):1621-7. doi: 10.1177/0363546507304719. Epub 2007 Jul 30. Am J Sports Med. 2007. PMID: 17664340
In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage.
Chu CR, Coyle CH, Chu CT, Szczodry M, Seshadri V, Karpie JC, Cieslak KM, Pringle EK. Chu CR, et al. Among authors: karpie jc. J Bone Joint Surg Am. 2010 Mar;92(3):599-608. doi: 10.2106/JBJS.I.00425. J Bone Joint Surg Am. 2010. PMID: 20194318 Free PMC article.
Optimizing CO2 normalizes pH and enhances chondrocyte viability during cold storage.
Dontchos BN, Coyle CH, Izzo NJ, Didiano DM, Karpie JC, Logar A, Chu CR. Dontchos BN, et al. Among authors: karpie jc. J Orthop Res. 2008 May;26(5):643-50. doi: 10.1002/jor.20534. J Orthop Res. 2008. PMID: 18050310 Free PMC article.
Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair.
Pagnotto MR, Wang Z, Karpie JC, Ferretti M, Xiao X, Chu CR. Pagnotto MR, et al. Among authors: karpie jc. Gene Ther. 2007 May;14(10):804-13. doi: 10.1038/ Epub 2007 Mar 8. Gene Ther. 2007. PMID: 17344902
Patellar tendon anterior cruciate ligament reconstruction in the high-demand patient: evaluation of autograft versus allograft reconstruction.
Mascarenhas R, Tranovich M, Karpie JC, Irrgang JJ, Fu FH, Harner CD. Mascarenhas R, et al. Among authors: karpie jc. Arthroscopy. 2010 Sep;26(9 Suppl):S58-66. doi: 10.1016/j.arthro.2010.01.004. Arthroscopy. 2010. PMID: 20810093