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Cause of and countermeasures for oxidation of the cysteine-derived reagent used in the amino acid derivative reactivity assay.
Fujita M, Yamamoto Y, Watanabe S, Sugawara T, Wakabayashi K, Tahara Y, Horie N, Fujimoto K, Kusakari K, Kurokawa Y, Kawakami T, Kojima K, Kojima H, Ono A, Katsuoka Y, Tanabe H, Yokoyama H, Kasahara T. Fujita M, et al. Among authors: kasahara t. J Appl Toxicol. 2019 Feb;39(2):191-208. doi: 10.1002/jat.3707. Epub 2018 Sep 16. J Appl Toxicol. 2019. PMID: 30221369
Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals.
Takenouchi O, Fukui S, Okamoto K, Kurotani S, Imai N, Fujishiro M, Kyotani D, Kato Y, Kasahara T, Fujita M, Toyoda A, Sekiya D, Watanabe S, Seto H, Hirota M, Ashikaga T, Miyazawa M. Takenouchi O, et al. Among authors: kasahara t. J Appl Toxicol. 2015 Nov;35(11):1318-32. doi: 10.1002/jat.3127. Epub 2015 Mar 29. J Appl Toxicol. 2015. PMID: 25820183
The within- and between-laboratory reproducibility and predictive capacity of the in chemico amino acid derivative reactivity assay: Results of validation study implemented in four participating laboratories.
Fujita M, Yamamoto Y, Watanabe S, Sugawara T, Wakabayashi K, Tahara Y, Horie N, Fujimoto K, Kusakari K, Kurokawa Y, Kawakami T, Kojima K, Sozu T, Nakayama T, Kusao T, Richmond J, Nicole K, Kim BH, Kojima H, Kasahara T, Ono A. Fujita M, et al. Among authors: kasahara t. J Appl Toxicol. 2019 Nov;39(11):1492-1505. doi: 10.1002/jat.3834. Epub 2019 Jul 17. J Appl Toxicol. 2019. PMID: 31313332
Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization.
Hirota M, Fukui S, Okamoto K, Kurotani S, Imai N, Fujishiro M, Kyotani D, Kato Y, Kasahara T, Fujita M, Toyoda A, Sekiya D, Watanabe S, Seto H, Takenouchi O, Ashikaga T, Miyazawa M. Hirota M, et al. Among authors: kasahara t. J Appl Toxicol. 2015 Nov;35(11):1333-47. doi: 10.1002/jat.3105. Epub 2015 Mar 30. J Appl Toxicol. 2015. PMID: 25824844
764 results