Kasembeli MM - Search Results

1

SH2 domain binding to phosphopeptide ligands: potential for drug targeting.

Kasembeli MM, Xu X, Tweardy DJ. Kasembeli MM, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14(3):1010-22. doi: 10.2741/3292. Front Biosci (Landmark Ed). 2009. PMID: 19273114 Free article. Review.

2

Chemical probes that competitively and selectively inhibit Stat3 activation.

Xu X, Kasembeli MM, Jiang X, Tweardy BJ, Tweardy DJ. Xu X, et al. Among authors: kasembeli mm. PLoS One. 2009;4(3):e4783. doi: 10.1371/journal.pone.0004783. Epub 2009 Mar 10. PLoS One. 2009. PMID: 19274102 Free PMC article.

3

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.

Kasembeli M, Lau WC, Roh SH, Eckols TK, Frydman J, Chiu W, Tweardy DJ. Kasembeli M, et al. PLoS Biol. 2014 Apr 22;12(4):e1001844. doi: 10.1371/journal.pbio.1001844. eCollection 2014 Apr. PLoS Biol. 2014. PMID: 24756126 Free PMC article.

4

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.

Bharadwaj U, Kasembeli MM, Eckols TK, Kolosov M, Lang P, Christensen K, Edwards DP, Tweardy DJ. Bharadwaj U, et al. Among authors: kasembeli mm. Cancers (Basel). 2014 Sep 29;6(4):2012-34. doi: 10.3390/cancers6042012. Cancers (Basel). 2014. PMID: 25268166 Free PMC article.

5

Contribution of chaperones to STAT pathway signaling.

Bocchini CE, Kasembeli MM, Roh SH, Tweardy DJ. Bocchini CE, et al. Among authors: kasembeli mm. JAKSTAT. 2014 Oct 30;3(3):e970459. doi: 10.4161/21623988.2014.970459. eCollection 2014. JAKSTAT. 2014. PMID: 26413421 Free PMC article. Review.

6

Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment.

Kasembeli MM, Bharadwaj U, Robinson P, Tweardy DJ. Kasembeli MM, et al. Int J Mol Sci. 2018 Aug 5;19(8):2299. doi: 10.3390/ijms19082299. Int J Mol Sci. 2018. PMID: 30081609 Free PMC article. Review.

7

Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility.

Kong R, Bharadwaj U, Eckols TK, Kolosov M, Wu H, Cruz-Pavlovich FJS, Shaw A, Ifelayo OI, Zhao H, Kasembeli MM, Wong STC, Tweardy DJ. Kong R, et al. Among authors: kasembeli mm. Pharmacol Res. 2021 Jul;169:105637. doi: 10.1016/j.phrs.2021.105637. Epub 2021 Apr 29. Pharmacol Res. 2021. PMID: 33932608 Free PMC article.

8

Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO.

Roh SH, Kasembeli M, Galaz-Montoya JG, Trnka M, Lau WC, Burlingame A, Chiu W, Tweardy DJ. Roh SH, et al. J Biol Chem. 2016 Feb 26;291(9):4732-41. doi: 10.1074/jbc.M115.684878. Epub 2015 Dec 24. J Biol Chem. 2016. PMID: 26706127 Free PMC article.

9

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer.

Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ. Bharadwaj U, et al. Among authors: kasembeli mm. Oncogene. 2015 Mar 12;34(11):1341-53. doi: 10.1038/onc.2014.72. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681959 Free PMC article.

10

Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.

Lewis KM, Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Fridley C, Siller R, Tweardy DJ. Lewis KM, et al. Among authors: kasembeli mm. Lung Cancer. 2015 Nov;90(2):182-90. doi: 10.1016/j.lungcan.2015.09.014. Epub 2015 Sep 15. Lung Cancer. 2015. PMID: 26410177 Free PMC article.

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