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A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness.
Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, Sato H, Komoto S, Narusaka T, Tomono Y, Xing B, Chen Y, Tazawa H, Kagawa S, Shirakawa Y, Kasai T, Seno M, Matsukawa A, Fujiwara T. Katsura Y, et al. Among authors: kashima h. Cancers (Basel). 2019 Feb 3;11(2):177. doi: 10.3390/cancers11020177. Cancers (Basel). 2019. PMID: 30717462 Free PMC article.
Iron depletion is a novel therapeutic strategy to target cancer stem cells.
Ninomiya T, Ohara T, Noma K, Katsura Y, Katsube R, Kashima H, Kato T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Chen L, Kasai T, Seno M, Matsukawa A, Fujiwara T. Ninomiya T, et al. Among authors: kashima h. Oncotarget. 2017 Oct 12;8(58):98405-98416. doi: 10.18632/oncotarget.21846. eCollection 2017 Nov 17. Oncotarget. 2017. PMID: 29228699 Free PMC article.
Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma.
Watanabe S, Noma K, Ohara T, Kashima H, Sato H, Kato T, Urano S, Katsube R, Hashimoto Y, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T. Watanabe S, et al. Among authors: kashima h. Cancer Biol Ther. 2019;20(9):1234-1248. doi: 10.1080/15384047.2019.1617566. Epub 2019 Jun 11. Cancer Biol Ther. 2019. PMID: 31185791 Free PMC article.
Fibroblast activation protein targeted near infrared photoimmunotherapy (NIR PIT) overcomes therapeutic resistance in human esophageal cancer.
Katsube R, Noma K, Ohara T, Nishiwaki N, Kobayashi T, Komoto S, Sato H, Kashima H, Kato T, Kikuchi S, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T. Katsube R, et al. Among authors: kashima h. Sci Rep. 2021 Jan 18;11(1):1693. doi: 10.1038/s41598-021-81465-4. Sci Rep. 2021. PMID: 33462372 Free PMC article.
Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (Telomelysin) with radiotherapy in oesophageal cancer patients unfit for standard treatments.
Shirakawa Y, Tazawa H, Tanabe S, Kanaya N, Noma K, Koujima T, Kashima H, Kato T, Kuroda S, Kikuchi S, Kagawa S, Katsui K, Kanazawa S, Urata Y, Fujiwara T. Shirakawa Y, et al. Among authors: kashima h. Eur J Cancer. 2021 Aug;153:98-108. doi: 10.1016/j.ejca.2021.04.043. Epub 2021 Jun 18. Eur J Cancer. 2021. PMID: 34153720 Free article. Clinical Trial.
Dual-targeted near-infrared photoimmunotherapy for esophageal cancer and cancer-associated fibroblasts in the tumor microenvironment.
Sato H, Noma K, Ohara T, Kawasaki K, Akai M, Kobayashi T, Nishiwaki N, Narusaka T, Komoto S, Kashima H, Katsura Y, Kato T, Kikuchi S, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T. Sato H, et al. Among authors: kashima h. Sci Rep. 2022 Nov 23;12(1):20152. doi: 10.1038/s41598-022-24313-3. Sci Rep. 2022. PMID: 36418422 Free PMC article.
366 results