Kastelein RA - Search Results

1

The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses.

Trinchieri G, Pflanz S, Kastelein RA. Trinchieri G, et al. Among authors: kastelein ra. Immunity. 2003 Nov;19(5):641-4. doi: 10.1016/s1074-7613(03)00296-6. Immunity. 2003. PMID: 14614851 Review.

2

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.

Wiekowski MT, Leach MW, Evans EW, Sullivan L, Chen SC, Vassileva G, Bazan JF, Gorman DM, Kastelein RA, Narula S, Lira SA. Wiekowski MT, et al. Among authors: kastelein ra. J Immunol. 2001 Jun 15;166(12):7563-70. doi: 10.4049/jimmunol.166.12.7563. J Immunol. 2001. PMID: 11390512

3

Interleukin-27: balancing protective and pathological immunity.

Hunter CA, Kastelein R. Hunter CA, et al. Immunity. 2012 Dec 14;37(6):960-9. doi: 10.1016/j.immuni.2012.11.003. Immunity. 2012. PMID: 23244718 Free PMC article. Review.

4

Immunomodulatory role of endogenous interleukin-18 in gamma interferon-mediated resolution of replicative Legionella pneumophila lung infection.

Brieland JK, Jackson C, Hurst S, Loebenberg D, Muchamuel T, Debets R, Kastelein R, Churakova T, Abrams J, Hare R, O'Garra A. Brieland JK, et al. Infect Immun. 2000 Dec;68(12):6567-73. doi: 10.1128/IAI.68.12.6567-6573.2000. Infect Immun. 2000. PMID: 11083766 Free PMC article.

5

Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii.

Cai G, Kastelein R, Hunter CA. Cai G, et al. Infect Immun. 2000 Dec;68(12):6932-8. doi: 10.1128/IAI.68.12.6932-6938.2000. Infect Immun. 2000. PMID: 11083816 Free PMC article.

6

Development, cytokine profile and function of human interleukin 17-producing helper T cells.

Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R. Wilson NJ, et al. Among authors: kastelein ra. Nat Immunol. 2007 Sep;8(9):950-7. doi: 10.1038/ni1497. Epub 2007 Aug 5. Nat Immunol. 2007. PMID: 17676044

7

Novel IL-12 family members shed light on the orchestration of Th1 responses.

Brombacher F, Kastelein RA, Alber G. Brombacher F, et al. Among authors: kastelein ra. Trends Immunol. 2003 Apr;24(4):207-12. doi: 10.1016/s1471-4906(03)00067-x. Trends Immunol. 2003. PMID: 12697453 Free PMC article. Review.

8

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection.

Villarino A, Hibbert L, Lieberman L, Wilson E, Mak T, Yoshida H, Kastelein RA, Saris C, Hunter CA. Villarino A, et al. Among authors: kastelein ra. Immunity. 2003 Nov;19(5):645-55. doi: 10.1016/s1074-7613(03)00300-5. Immunity. 2003. PMID: 14614852

9

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis.

Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S, Lucian L, Geissler R, Brodie S, Kimball AB, Gorman DM, Smith K, de Waal Malefyt R, Kastelein RA, McClanahan TK, Bowman EP. Chan JR, et al. Among authors: kastelein ra. J Exp Med. 2006 Nov 27;203(12):2577-87. doi: 10.1084/jem.20060244. Epub 2006 Oct 30. J Exp Med. 2006. PMID: 17074928 Free PMC article.

10

IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells.

Diveu C, McGeachy MJ, Boniface K, Stumhofer JS, Sathe M, Joyce-Shaikh B, Chen Y, Tato CM, McClanahan TK, de Waal Malefyt R, Hunter CA, Cua DJ, Kastelein RA. Diveu C, et al. Among authors: kastelein ra. J Immunol. 2009 May 1;182(9):5748-56. doi: 10.4049/jimmunol.0801162. J Immunol. 2009. PMID: 19380822

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