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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 1
1997 2
1998 1
1999 1
2000 2
2001 3
2002 3
2003 5
2004 4
2005 1
2006 2
2008 2
2009 3
2010 2
2012 5
2013 2
2014 1
2015 2
2016 3
2017 2
2018 4
2019 3
2020 0
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Page 1
CRTAM determines the CD4+ cytotoxic T lymphocyte lineage.
Takeuchi A, et al. J Exp Med 2016. Among authors: Katakai T. PMID 26694968 Free PMC article.
Naive T cells differentiate into various effector T cells, including CD4(+) helper T cell subsets and CD8(+) cytotoxic T cells (CTL). Although cytotoxic CD4(+) T cells (CD4 +: CTL) also develop from naive T cells, the mechanism of development is elusive. We found that a small fraction of CD4(+) T cells that express class I-restricted T cell-associated molecule (CRTAM) upon activation possesses the characteristics of both CD4(+) and CD8(+) T cells. ...
Naive T cells differentiate into various effector T cells, including CD4(+) helper T cell subsets and CD8(+) cytotoxic …
Visualizing the Rapid and Dynamic Elimination of Allogeneic T Cells in Secondary Lymphoid Organs.
Kanda Y, et al. J Immunol 2018. Among authors: Katakai T. PMID 29925676 Free article.
However, the rejection process of allogeneic T (allo-T) cells is poorly understood. In this study, using fluorescence-based monitoring and two-photon live imaging in mouse adoptive transfer system, we visualized the fate of allo-T cells in the in vivo environment and showed rapid elimination in secondary lymphoid organs (SLOs). ...At early time points, allo-T cells robustly migrated in the T cell area, whereas after 8 h, the numbers of arrested cells and cell fragments were dramatically elevated. ...
However, the rejection process of allogeneic T (allo-T) cells is poorly understood. In this study, using fluorescence-based mo …
Novel Targeting to XCR1(+) Dendritic Cells Using Allogeneic T Cells for Polytopical Antibody Responses in the Lymph Nodes.
Kitazawa Y, et al. Front Immunol 2019. Among authors: Katakai T. PMID 31191552 Free PMC article.
Among the donor blood components, T cells were the most efficient immunogens, inducing recipient T cell and B cell proliferative responses not only in the spleen, but also in the peripheral and gut LNs. Donor T cells soon migrated to the splenic T cell area and the LNs, with a temporary significant increase in recipient NK cells. ...
Among the donor blood components, T cells were the most efficient immunogens, inducing recipient T cell and B cell proliferati …
Essential role of CCL21 in establishment of central self-tolerance in T cells.
Kozai M, et al. J Exp Med 2017. Among authors: Katakai T. PMID 28611158 Free PMC article.
The chemokine receptor CCR7 directs T cell relocation into and within lymphoid organs, including the migration of developing thymocytes into the thymic medulla. ...T cell accumulation in the lymph nodes was also defective. These results indicate a nonredundant role of CCL21Ser in the establishment of self-tolerance in T cells in the thymic medulla, and reveal a functional inequality among CCR7 ligands in vivo....
The chemokine receptor CCR7 directs T cell relocation into and within lymphoid organs, including the migration of developing thymocyt …
Live Imaging of Interstitial T Cell Migration Using Lymph Node Slices.
Katakai T. Methods Mol Biol 2018. PMID 29476486
Interstitial T cell migration in the lymph node (LN) is a phenomenon intensively examined using TP-LSM in the field of immunology. Intravital and explant methods have been standards for imaging T cell behaviors in the LN, though there are several limitations. ...
Interstitial T cell migration in the lymph node (LN) is a phenomenon intensively examined using TP-LSM in the field of immunology. In …
Microenvironmental Control of High-Speed Interstitial T Cell Migration in the Lymph Node.
Katakai T and Kinashi T. Front Immunol 2016. PMID 27242799 Free PMC article.
T cells are highly concentrated in the lymph node (LN) paracortex, which serves an important role in triggering adoptive immune responses. ...We propose that T cells dynamically switch between two motility modes; anchorage-dependent and -independent manners. Unique tissue microenvironment and characteristic migration modality of T cells cooperatively generate high-speed interstitial movement in the LN....
T cells are highly concentrated in the lymph node (LN) paracortex, which serves an important role in triggering adoptive immune respo
Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs
Bogdanova D, et al. J Immunol 2018. Among authors: Katakai T. PMID 30397032 Free article.
Instead, the T cell area was severely disturbed by the lack of CCL21-expressing FSCs, whereas the follicles and associated FSC networks were formed. ...
Instead, the T cell area was severely disturbed by the lack of CCL21-expressing FSCs, whereas the follicles and associated FSC networ …
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