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Structure, assembly and inhibition of the Toxoplasma gondii respiratory chain supercomplex.
MacLean AE, Shikha S, Ferreira Silva M, Gramelspacher MJ, Nilsen A, Liebman KM, Pou S, Winter RW, Meir A, Riscoe MK, Doggett JS, Sheiner L, Mühleip A. MacLean AE, et al. Among authors: liebman km. Nat Struct Mol Biol. 2025 Aug;32(8):1424-1433. doi: 10.1038/s41594-025-01531-7. Epub 2025 May 19. Nat Struct Mol Biol. 2025. PMID: 40389671 Free PMC article.
Synthesis of Deuterated Endochin-Like Quinolones.
Pou S, Winter RW, Liebman KM, Dodean RA, Nilsen A, DeBarber A, Doggett JS, Riscoe MK. Pou S, et al. Among authors: liebman km. J Labelled Comp Radiopharm. 2024 May 15;67(5):186-196. doi: 10.1002/jlcr.4092. Epub 2024 Apr 25. J Labelled Comp Radiopharm. 2024. PMID: 38661253 Free PMC article.
Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.
Dodean RA, Li Y, Zhang X, Caridha D, Madejczyk MS, Jin X, Dennis WE, Chetree R, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca J, Vuong C, Pannone K, Dinh HT, Mdaki K, Leed S, Martin ML, Pybus BS, Pou S, Winter RW, Liebman KM, Williams R, Kumar A, Chim-Ong A, Cui L, Orena S, Assimwe J, Tibagambirwa I, Byaruhanga O, Angutoko P, Legac J, Kreutzfeld O, Rosenthal PJ, Cooper RA, Nilsen A, Riscoe MK, Roth A, Kancharla P, Kelly JX. Dodean RA, et al. Among authors: liebman km. J Med Chem. 2025 Apr 24;68(8):8817-8840. doi: 10.1021/acs.jmedchem.5c00419. Epub 2025 Apr 3. J Med Chem. 2025. PMID: 40179277 Free PMC article.
Acridone Prodrugs with Enhanced Dual-Stage Antimalarial Efficacy.
Dodean RA, Li Y, Zhang X, Kumar A, Pou S, W Winter R, Liebman KM, Zakharov LN, Caridha D, Madejczyk MS, Vuong C, DeLuca J, Chin G, Kudyba K, McEnearney S, Jin X, Dennis WE, Chetree R, Blount C, Pannone K, Dinh HT, Mdaki K, Leed S, Lee PJ, Roth A, Kancharla P, Kelly JX. Dodean RA, et al. Among authors: liebman km. ACS Med Chem Lett. 2025 Jun 6;16(7):1383-1390. doi: 10.1021/acsmedchemlett.5c00251. eCollection 2025 Jul 10. ACS Med Chem Lett. 2025. PMID: 40666482
A New Scalable Synthesis of ELQ-300, ELQ-316, and other Antiparasitic Quinolones.
Pou S, Dodean RA, Frueh L, Liebman KM, Gallagher RT, Jin H, Jacobs RT, Nilsen A, Stuart DR, Doggett JS, Riscoe MK, Winter RW. Pou S, et al. Among authors: liebman km. Org Process Res Dev. 2021 Aug 20;25(8):1841-1852. doi: 10.1021/acs.oprd.1c00099. Epub 2021 Aug 4. Org Process Res Dev. 2021. PMID: 35110959 Free PMC article.