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Page 1
CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages.
Poglitsch M, Weichhart T, Hecking M, Werzowa J, Katholnig K, Antlanger M, Krmpotic A, Jonjic S, Hörl WH, Zlabinger GJ, Puchhammer E, Säemann MD. Poglitsch M, et al. Among authors: katholnig k. Am J Transplant. 2012 Jun;12(6):1458-68. doi: 10.1111/j.1600-6143.2012.04002.x. Epub 2012 Mar 5. Am J Transplant. 2012. PMID: 22390651 Free article.
Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression.
Linke M, Pham HT, Katholnig K, Schnöller T, Miller A, Demel F, Schütz B, Rosner M, Kovacic B, Sukhbaatar N, Niederreiter B, Blüml S, Kuess P, Sexl V, Müller M, Mikula M, Weckwerth W, Haschemi A, Susani M, Hengstschläger M, Gambello MJ, Weichhart T. Linke M, et al. Among authors: katholnig k. Nat Immunol. 2017 Mar;18(3):293-302. doi: 10.1038/ni.3655. Epub 2017 Jan 16. Nat Immunol. 2017. PMID: 28092373 Free PMC article.
Serum amyloid A in uremic HDL promotes inflammation.
Weichhart T, Kopecky C, Kubicek M, Haidinger M, Döller D, Katholnig K, Suarna C, Eller P, Tölle M, Gerner C, Zlabinger GJ, van der Giet M, Hörl WH, Stocker R, Säemann MD. Weichhart T, et al. Among authors: katholnig k. J Am Soc Nephrol. 2012 May;23(5):934-47. doi: 10.1681/ASN.2011070668. Epub 2012 Jan 26. J Am Soc Nephrol. 2012. PMID: 22282592 Free PMC article.
Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T. Katholnig K, et al. JCI Insight. 2019 Oct 17;4(20):e124164. doi: 10.1172/jci.insight.124164. JCI Insight. 2019. PMID: 31619583 Free PMC article.
Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.
Wilson JL, Nägele T, Linke M, Demel F, Fritsch SD, Mayr HK, Cai Z, Katholnig K, Sun X, Fragner L, Miller A, Haschemi A, Popa A, Bergthaler A, Hengstschläger M, Weichhart T, Weckwerth W. Wilson JL, et al. Among authors: katholnig k. Cell Rep. 2020 Feb 4;30(5):1542-1552.e7. doi: 10.1016/j.celrep.2020.01.011. Cell Rep. 2020. PMID: 32023468 Free PMC article.