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Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormone.
Shinagawa Y, Inoue T, Katsushima T, Kiguchi T, Ikenogami T, Ogawa N, Fukuda K, Hirata K, Harada K, Takagi M, Nakagawa T, Kimura S, Matsuo Y, Maekawa M, Hayashi M, Soejima Y, Takahashi M, Shindo M, Hashimoto H. Shinagawa Y, et al. Among authors: katsushima t. ACS Med Chem Lett. 2010 Dec 29;2(3):238-42. doi: 10.1021/ml100268k. eCollection 2011 Mar 10. ACS Med Chem Lett. 2010. PMID: 24900301 Free PMC article.
Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]phenyl}acetyloxymethyl)-2-phenylmalonate (JTT-130), an intestine-specific inhibitor of microsomal triglyceride transfer protein.
Mera Y, Odani N, Kawai T, Hata T, Suzuki M, Hagiwara A, Katsushima T, Kakutani M. Mera Y, et al. Among authors: katsushima t. J Pharmacol Exp Ther. 2011 Feb;336(2):321-7. doi: 10.1124/jpet.110.173807. Epub 2010 Oct 25. J Pharmacol Exp Ther. 2011. PMID: 20974698