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The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea.
Pereda A, Summers RG, Stassi DL, Ruan X, Katz L. Pereda A, et al. Microbiology. 1998 Feb;144 ( Pt 2):543-53. doi: 10.1099/00221287-144-2-543. Microbiology. 1998. PMID: 9493390
Module 1 is preceded by loading acyltransferase (AT-L) and acyl carrier protein (ACP-L) domains, hypothesized to initiate polyketide chain growth with a propionate-derived moiety. Using recombinant DNA technology several mutant strains of Saccharopolyspora erythraea …
Module 1 is preceded by loading acyltransferase (AT-L) and acyl carrier protein (ACP-L) domains, hypothesized to initiate poly …
Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
Ruan X, Pereda A, Stassi DL, Zeidner D, Summers RG, Jackson M, Shivakumar A, Kakavas S, Staver MJ, Donadio S, Katz L. Ruan X, et al. J Bacteriol. 1997 Oct;179(20):6416-25. doi: 10.1128/jb.179.20.6416-6425.1997. J Bacteriol. 1997. PMID: 9335291 Free PMC article.
Katz L, Donadio S. Katz L, et al. Biotechnology. 1995;28:385-420. doi: 10.1016/b978-0-7506-9095-9.50023-x. Biotechnology. 1995. PMID: 8688632 Review. No abstract available.
An erythromycin analog produced by reprogramming of polyketide synthesis.
Donadio S, McAlpine JB, Sheldon PJ, Jackson M, Katz L. Donadio S, et al. Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7119-23. doi: 10.1073/pnas.90.15.7119. Proc Natl Acad Sci U S A. 1993. PMID: 8346223 Free PMC article.
Gene dosage effect on the expression of the delta-endotoxin genes of Bacillus thuringiensis subsp. kurstaki in Bacillus subtilis and Bacillus megaterium.
Shivakumar AG, Vanags RI, Wilcox DR, Katz L, Vary PS, Fox JL. Shivakumar AG, et al. Gene. 1989 Jun 30;79(1):21-31. doi: 10.1016/0378-1119(89)90089-9. Gene. 1989. PMID: 2550328
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