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Subcutaneous checkpoint inhibition is equivalent to systemic delivery when combined with nelitolimod delivered via pressure-enabled drug delivery for depletion of intrahepatic myeloid-derived suppressor cells and control of liver metastases.
Ghosh CC, Cournoyer L, Liu Y, Ballarin A, Layman IB, LaPorte J, Morrissey M, Fraser K, Perati S, Cox BF, Yakirevich E, Treaba DO, Murtha TD, Guha P, Katz SC, Davar D. Ghosh CC, et al. Among authors: katz sc. J Immunother Cancer. 2024 Jul 22;12(7):e008837. doi: 10.1136/jitc-2024-008837. J Immunother Cancer. 2024. PMID: 39038918 Free PMC article.
Novel treatment paradigms for metastatic uveal melanoma.
Patel SP, Katz SC. Patel SP, et al. Among authors: katz sc. Cancer Gene Ther. 2022 Dec;29(12):1807-1808. doi: 10.1038/s41417-022-00558-y. Epub 2022 Dec 1. Cancer Gene Ther. 2022. PMID: 36456705 Free PMC article. No abstract available.
Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases.
Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG. Sullivan KM, et al. Among authors: katz sc. Gut. 2023 Feb;72(2):325-337. doi: 10.1136/gutjnl-2021-325808. Epub 2022 Jun 15. Gut. 2023. PMID: 35705369 Free PMC article.
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition.
Ghosh CC, Heatherton KR, Connell KPO, Alexander IS, Greer DA, LaPorte J, Guha P, Cox BF, Katz SC. Ghosh CC, et al. Among authors: katz sc. Cancer Gene Ther. 2022 Dec;29(12):1854-1865. doi: 10.1038/s41417-022-00484-z. Epub 2022 Jun 14. Cancer Gene Ther. 2022. PMID: 35697801 Free PMC article.
Assessing the Future of Solid Tumor Immunotherapy.
Guha P, Heatherton KR, O'Connell KP, Alexander IS, Katz SC. Guha P, et al. Among authors: katz sc. Biomedicines. 2022 Mar 11;10(3):655. doi: 10.3390/biomedicines10030655. Biomedicines. 2022. PMID: 35327456 Free PMC article. Review.
87 results