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Page 1
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes.
Keymeulen B, Vandemeulebroucke E, Ziegler AG, Mathieu C, Kaufman L, Hale G, Gorus F, Goldman M, Walter M, Candon S, Schandene L, Crenier L, De Block C, Seigneurin JM, De Pauw P, Pierard D, Weets I, Rebello P, Bird P, Berrie E, Frewin M, Waldmann H, Bach JF, Pipeleers D, Chatenoud L. Keymeulen B, et al. Among authors: kaufman l. N Engl J Med. 2005 Jun 23;352(25):2598-608. doi: 10.1056/NEJMoa043980. N Engl J Med. 2005. PMID: 15972866 Free article. Clinical Trial.
Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.
Keymeulen B, Walter M, Mathieu C, Kaufman L, Gorus F, Hilbrands R, Vandemeulebroucke E, Van de Velde U, Crenier L, De Block C, Candon S, Waldmann H, Ziegler AG, Chatenoud L, Pipeleers D. Keymeulen B, et al. Among authors: kaufman l. Diabetologia. 2010 Apr;53(4):614-23. doi: 10.1007/s00125-009-1644-9. Epub 2010 Jan 14. Diabetologia. 2010. PMID: 20225393 Clinical Trial.
Relation between disease phenotype and HLA-DQ genotype in diabetic patients diagnosed in early adulthood.
Weets I, Siraux V, Daubresse JC, De Leeuw IH, Féry F, Keymeulen B, Krzentowski G, Letiexhe M, Mathieu C, Nobels F, Rottiers R, Scheen A, Van Gaal L, Schuit FC, Van der Auwera B, Rui M, De Pauw P, Kaufman L, Gorus FK; Belgian Diabetes Registry. Weets I, et al. Among authors: kaufman l. J Clin Endocrinol Metab. 2002 Jun;87(6):2597-605. doi: 10.1210/jcem.87.6.8613. J Clin Endocrinol Metab. 2002. PMID: 12050221 Free article.
Preexisting insulin autoantibodies predict efficacy of otelixizumab in preserving residual β-cell function in recent-onset type 1 diabetes.
Demeester S, Keymeulen B, Kaufman L, Van Dalem A, Balti EV, Van de Velde U, Goubert P, Verhaeghen K, Davidson HW, Wenzlau JM, Weets I, Pipeleers DG, Gorus FK. Demeester S, et al. Among authors: kaufman l. Diabetes Care. 2015 Apr;38(4):644-51. doi: 10.2337/dc14-1575. Epub 2015 Jan 12. Diabetes Care. 2015. PMID: 25583753 Free PMC article. Clinical Trial.
Use of an islet cell antibody assay to identify type 1 diabetic patients with rapid decrease in C-peptide levels after clinical onset. Belgian Diabetes Registry.
Decochez K, Keymeulen B, Somers G, Dorchy H, De Leeuw IH, Mathieu C, Rottiers R, Winnock F, ver Elst K, Weets I, Kaufman L, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Decochez K, et al. Among authors: kaufman l. Diabetes Care. 2000 Aug;23(8):1072-8. doi: 10.2337/diacare.23.8.1072. Diabetes Care. 2000. PMID: 10937500
IA-2 autoantibodies predict impending type I diabetes in siblings of patients.
Decochez K, De Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Weets I, Vandemeulebroucke E, Truyen I, Kaufman L, Schuit FC, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Decochez K, et al. Among authors: kaufman l. Diabetologia. 2002 Dec;45(12):1658-66. doi: 10.1007/s00125-002-0949-8. Epub 2002 Nov 12. Diabetologia. 2002. PMID: 12488955
Seasonality in clinical onset of type 1 diabetes in belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence.
Weets I, Kaufman L, Van der Auwera B, Crenier L, Rooman RP, De Block C, Casteels K, Weber E, Coeckelberghs M, Laron Z, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Weets I, et al. Among authors: kaufman l. Diabetologia. 2004 Apr;47(4):614-21. doi: 10.1007/s00125-004-1369-8. Diabetologia. 2004. PMID: 15298337
Identification of prediabetes in first-degree relatives at intermediate risk of type I diabetes.
Truyen I, De Grijse J, Weets I, Kaufman L, Pipeleers L, Nanos N, Decochez K, Hilbrands R, Kaufman JM, Keymeulen B, Mathieu C, Van Gaal L, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Truyen I, et al. Among authors: kaufman l, kaufman jm. Clin Exp Immunol. 2007 Aug;149(2):243-50. doi: 10.1111/j.1365-2249.2007.03416.x. Epub 2007 May 22. Clin Exp Immunol. 2007. PMID: 17521324 Free PMC article.
Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients.
Hilbrands R, Huurman VA, Gillard P, Velthuis JH, De Waele M, Mathieu C, Kaufman L, Pipeleers-Marichal M, Ling Z, Movahedi B, Jacobs-Tulleneers-Thevissen D, Monbaliu D, Ysebaert D, Gorus FK, Roep BO, Pipeleers DG, Keymeulen B. Hilbrands R, et al. Among authors: kaufman l. Diabetes. 2009 Oct;58(10):2267-76. doi: 10.2337/db09-0160. Epub 2009 Jul 14. Diabetes. 2009. PMID: 19602536 Free PMC article.
1,056 results