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490 results
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Regulation of mRNA translation by protein folding in the endoplasmic reticulum.
Kaufman RJ. Kaufman RJ. Trends Biochem Sci. 2004 Mar;29(3):152-8. doi: 10.1016/j.tibs.2004.01.004. Trends Biochem Sci. 2004. PMID: 15003273 Review.
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. Lee K, et al. Among authors: kaufman rj. Genes Dev. 2002 Feb 15;16(4):452-66. doi: 10.1101/gad.964702. Genes Dev. 2002. PMID: 11850408 Free PMC article.
Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum.
Wu S, Hu Y, Wang JL, Chatterjee M, Shi Y, Kaufman RJ. Wu S, et al. Among authors: kaufman rj. J Biol Chem. 2002 May 17;277(20):18077-83. doi: 10.1074/jbc.M110164200. Epub 2002 Mar 4. J Biol Chem. 2002. PMID: 11877419
The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain.
Liu CY, Wong HN, Schauerte JA, Kaufman RJ. Liu CY, et al. Among authors: kaufman rj. J Biol Chem. 2002 May 24;277(21):18346-56. doi: 10.1074/jbc.M112454200. Epub 2002 Mar 15. J Biol Chem. 2002. PMID: 11897784
The unfolded protein response in nutrient sensing and differentiation.
Kaufman RJ, Scheuner D, Schröder M, Shen X, Lee K, Liu CY, Arnold SM. Kaufman RJ, et al. Nat Rev Mol Cell Biol. 2002 Jun;3(6):411-21. doi: 10.1038/nrm829. Nat Rev Mol Cell Biol. 2002. PMID: 12042763 Review.
Orchestrating the unfolded protein response in health and disease.
Kaufman RJ. Kaufman RJ. J Clin Invest. 2002 Nov;110(10):1389-98. doi: 10.1172/JCI16886. J Clin Invest. 2002. PMID: 12438434 Free PMC article. Review. No abstract available.
The unfolded protein response is required for haploid tolerance in yeast.
Lee K, Neigeborn L, Kaufman RJ. Lee K, et al. Among authors: kaufman rj. J Biol Chem. 2003 Apr 4;278(14):11818-27. doi: 10.1074/jbc.M210475200. Epub 2003 Jan 30. J Biol Chem. 2003. PMID: 12560331
Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha.
Liu CY, Xu Z, Kaufman RJ. Liu CY, et al. Among authors: kaufman rj. J Biol Chem. 2003 May 16;278(20):17680-7. doi: 10.1074/jbc.M300418200. Epub 2003 Mar 13. J Biol Chem. 2003. PMID: 12637535
All roads lead to ATF4.
Rutkowski DT, Kaufman RJ. Rutkowski DT, et al. Among authors: kaufman rj. Dev Cell. 2003 Apr;4(4):442-4. doi: 10.1016/s1534-5807(03)00100-x. Dev Cell. 2003. PMID: 12689582 Review.
The unfolded protein response.
Liu CY, Kaufman RJ. Liu CY, et al. Among authors: kaufman rj. J Cell Sci. 2003 May 15;116(Pt 10):1861-2. doi: 10.1242/jcs.00408. J Cell Sci. 2003. PMID: 12692187 Review. No abstract available.
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