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Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II.
Yamamoto K, Yoshida H, Kokame K, Kaufman RJ, Mori K. Yamamoto K, et al. Among authors: kaufman rj. J Biochem. 2004 Sep;136(3):343-50. doi: 10.1093/jb/mvh122. J Biochem. 2004. PMID: 15598891
Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation.
Nagasawa K, Higashi T, Hosokawa N, Kaufman RJ, Nagata K. Nagasawa K, et al. Among authors: kaufman rj. EMBO Rep. 2007 May;8(5):483-9. doi: 10.1038/sj.embor.7400933. Epub 2007 Mar 23. EMBO Rep. 2007. PMID: 17380188 Free PMC article.
Regulation of ERGIC-53 gene transcription in response to endoplasmic reticulum stress.
Renna M, Caporaso MG, Bonatti S, Kaufman RJ, Remondelli P. Renna M, et al. Among authors: kaufman rj. J Biol Chem. 2007 Aug 3;282(31):22499-512. doi: 10.1074/jbc.M703778200. Epub 2007 May 29. J Biol Chem. 2007. PMID: 17535801
Protein misfolding in the endoplasmic reticulum as a conduit to human disease.
Wang M, Kaufman RJ. Wang M, et al. Among authors: kaufman rj. Nature. 2016 Jan 21;529(7586):326-35. doi: 10.1038/nature17041. Nature. 2016. PMID: 26791723 Review.
Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress.
D'Osualdo A, Anania VG, Yu K, Lill JR, Kaufman RJ, Matsuzawa S, Reed JC. D'Osualdo A, et al. Among authors: kaufman rj. PLoS One. 2015 Jun 18;10(6):e0130635. doi: 10.1371/journal.pone.0130635. eCollection 2015. PLoS One. 2015. PMID: 26086088 Free PMC article.
How does protein misfolding in the endoplasmic reticulum affect lipid metabolism in the liver?
Wang S, Kaufman RJ. Wang S, et al. Among authors: kaufman rj. Curr Opin Lipidol. 2014 Apr;25(2):125-32. doi: 10.1097/MOL.0000000000000056. Curr Opin Lipidol. 2014. PMID: 24565920 Review.
Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response.
Misra J, Kim DK, Choi W, Koo SH, Lee CH, Back SH, Kaufman RJ, Choi HS. Misra J, et al. Among authors: kaufman rj. Nucleic Acids Res. 2013 Aug;41(14):6960-74. doi: 10.1093/nar/gkt429. Epub 2013 May 28. Nucleic Acids Res. 2013. PMID: 23716639 Free PMC article.
Endoplasmic reticulum stress in liver disease.
Malhi H, Kaufman RJ. Malhi H, et al. Among authors: kaufman rj. J Hepatol. 2011 Apr;54(4):795-809. doi: 10.1016/j.jhep.2010.11.005. Epub 2010 Nov 13. J Hepatol. 2011. PMID: 21145844 Free PMC article. Review.
Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.
Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA. Luebke-Wheeler J, et al. Among authors: kaufman rj. Hepatology. 2008 Oct;48(4):1242-50. doi: 10.1002/hep.22439. Hepatology. 2008. PMID: 18704925 Free PMC article.
Achromatopsia mutations target sequential steps of ATF6 activation.
Chiang WC, Chan P, Wissinger B, Vincent A, Skorczyk-Werner A, Krawczyński MR, Kaufman RJ, Tsang SH, Héon E, Kohl S, Lin JH. Chiang WC, et al. Among authors: kaufman rj. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):400-405. doi: 10.1073/pnas.1606387114. Epub 2016 Dec 27. Proc Natl Acad Sci U S A. 2017. PMID: 28028229 Free PMC article.
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