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The mammalian unfolded protein response.
Schröder M, Kaufman RJ. Schröder M, et al. Annu Rev Biochem. 2005;74:739-89. doi: 10.1146/annurev.biochem.73.011303.074134. Annu Rev Biochem. 2005. PMID: 15952902 Review.
Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response.
Zhang C, Cai Y, Adachi MT, Oshiro S, Aso T, Kaufman RJ, Kitajima S. Zhang C, et al. J Biol Chem. 2001 Sep 21;276(38):35867-74. doi: 10.1074/jbc.M100747200. Epub 2001 Jul 10. J Biol Chem. 2001. PMID: 11447214
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. Lee K, et al. Genes Dev. 2002 Feb 15;16(4):452-66. doi: 10.1101/gad.964702. Genes Dev. 2002. PMID: 11850408 Free PMC article.
Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum.
Wu S, Hu Y, Wang JL, Chatterjee M, Shi Y, Kaufman RJ. Wu S, et al. J Biol Chem. 2002 May 17;277(20):18077-83. doi: 10.1074/jbc.M110164200. Epub 2002 Mar 4. J Biol Chem. 2002. PMID: 11877419
The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain.
Liu CY, Wong HN, Schauerte JA, Kaufman RJ. Liu CY, et al. J Biol Chem. 2002 May 24;277(21):18346-56. doi: 10.1074/jbc.M112454200. Epub 2002 Mar 15. J Biol Chem. 2002. PMID: 11897784
The unfolded protein response in nutrient sensing and differentiation.
Kaufman RJ, Scheuner D, Schröder M, Shen X, Lee K, Liu CY, Arnold SM. Kaufman RJ, et al. Nat Rev Mol Cell Biol. 2002 Jun;3(6):411-21. doi: 10.1038/nrm829. Nat Rev Mol Cell Biol. 2002. PMID: 12042763 Review.
Orchestrating the unfolded protein response in health and disease.
Kaufman RJ. Kaufman RJ. J Clin Invest. 2002 Nov;110(10):1389-98. doi: 10.1172/JCI16886. J Clin Invest. 2002. PMID: 12438434 Free PMC article. Review. No abstract available.
The unfolded protein response is required for haploid tolerance in yeast.
Lee K, Neigeborn L, Kaufman RJ. Lee K, et al. J Biol Chem. 2003 Apr 4;278(14):11818-27. doi: 10.1074/jbc.M210475200. Epub 2003 Jan 30. J Biol Chem. 2003. PMID: 12560331
A time-dependent phase shift in the mammalian unfolded protein response.
Yoshida H, Matsui T, Hosokawa N, Kaufman RJ, Nagata K, Mori K. Yoshida H, et al. Dev Cell. 2003 Feb;4(2):265-71. doi: 10.1016/s1534-5807(03)00022-4. Dev Cell. 2003. PMID: 12586069
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