Kaur S - Search Results

1

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.

Shen BQ, Xu K, Liu L, Raab H, Bhakta S, Kenrick M, Parsons-Reponte KL, Tien J, Yu SF, Mai E, Li D, Tibbitts J, Baudys J, Saad OM, Scales SJ, McDonald PJ, Hass PE, Eigenbrot C, Nguyen T, Solis WA, Fuji RN, Flagella KM, Patel D, Spencer SD, Khawli LA, Ebens A, Wong WL, Vandlen R, Kaur S, Sliwkowski MX, Scheller RH, Polakis P, Junutula JR. Shen BQ, et al. Among authors: kaur s. Nat Biotechnol. 2012 Jan 22;30(2):184-9. doi: 10.1038/nbt.2108. Nat Biotechnol. 2012. PMID: 22267010

2

Characterization of intact antibody-drug conjugates from plasma/serum in vivo by affinity capture capillary liquid chromatography-mass spectrometry.

Xu K, Liu L, Saad OM, Baudys J, Williams L, Leipold D, Shen B, Raab H, Junutula JR, Kim A, Kaur S. Xu K, et al. Among authors: kaur s. Anal Biochem. 2011 May 1;412(1):56-66. doi: 10.1016/j.ab.2011.01.004. Epub 2011 Jan 7. Anal Biochem. 2011. PMID: 21216214

3

Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats.

Boswell CA, Mundo EE, Zhang C, Bumbaca D, Valle NR, Kozak KR, Fourie A, Chuh J, Koppada N, Saad O, Gill H, Shen BQ, Rubinfeld B, Tibbitts J, Kaur S, Theil FP, Fielder PJ, Khawli LA, Lin K. Boswell CA, et al. Among authors: kaur s. Bioconjug Chem. 2011 Oct 19;22(10):1994-2004. doi: 10.1021/bc200212a. Epub 2011 Oct 3. Bioconjug Chem. 2011. PMID: 21913715

4

Catabolic fate and pharmacokinetic characterization of trastuzumab emtansine (T-DM1): an emphasis on preclinical and clinical catabolism.

Shen BQ, Bumbaca D, Saad O, Yue Q, Pastuskovas CV, Khojasteh SC, Tibbitts J, Kaur S, Wang B, Chu YW, LoRusso PM, Girish S. Shen BQ, et al. Among authors: kaur s. Curr Drug Metab. 2012 Sep 1;13(7):901-10. doi: 10.2174/138920012802138598. Curr Drug Metab. 2012. PMID: 22475269

5

Overcoming soluble target interference in an anti-therapeutic antibody screening assay for an antibody-drug conjugate therapeutic.

Carrasco-Triguero M, Mahood C, Milojic-Blair M, Amaya C, Ruppel J, Hong K, Yi JH, Kaur S. Carrasco-Triguero M, et al. Among authors: kaur s. Bioanalysis. 2012 Aug;4(16):2013-26. doi: 10.4155/bio.12.165. Bioanalysis. 2012. PMID: 22946917

6

American Association of Pharmaceutical Scientists National Biotechnology Conference Short Course: Translational Challenges in Developing Antibody-Drug Conjugates: May 24, 2012, San Diego, CA.

Thudium K, Bilic S, Leipold D, Mallet W, Kaur S, Meibohm B, Erickson H, Tibbitts J, Zhao H, Gupta M. Thudium K, et al. Among authors: kaur s. MAbs. 2013 Jan-Feb;5(1):5-12. doi: 10.4161/mabs.22909. Epub 2012 Dec 19. MAbs. 2013. PMID: 23255090 Free PMC article.

7

Bioanalytical assay strategies for the development of antibody-drug conjugate biotherapeutics.

Kaur S, Xu K, Saad OM, Dere RC, Carrasco-Triguero M. Kaur S, et al. Bioanalysis. 2013 Jan;5(2):201-26. doi: 10.4155/bio.12.299. Bioanalysis. 2013. PMID: 23330562

8

Immunogenicity assays for antibody-drug conjugates: case study with ado-trastuzumab emtansine.

Carrasco-Triguero M, Yi JH, Dere R, Qiu ZJ, Lei C, Li Y, Mahood C, Wang B, Leipold D, Poon KA, Kaur S. Carrasco-Triguero M, et al. Among authors: kaur s. Bioanalysis. 2013 May;5(9):1007-23. doi: 10.4155/bio.13.64. Bioanalysis. 2013. PMID: 23641693

9

PK assays for antibody-drug conjugates: case study with ado-trastuzumab emtansine.

Dere R, Yi JH, Lei C, Saad OM, Huang C, Li Y, Baudys J, Kaur S. Dere R, et al. Among authors: kaur s. Bioanalysis. 2013 May;5(9):1025-40. doi: 10.4155/bio.13.72. Bioanalysis. 2013. PMID: 23641694

10

Characterization of the drug-to-antibody ratio distribution for antibody-drug conjugates in plasma/serum.

Xu K, Liu L, Dere R, Mai E, Erickson R, Hendricks A, Lin K, Junutula JR, Kaur S. Xu K, et al. Among authors: kaur s. Bioanalysis. 2013 May;5(9):1057-71. doi: 10.4155/bio.13.66. Bioanalysis. 2013. PMID: 23641696

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