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Spontaneous and induced nontransgenic animal models of AD: modeling AD using combinatorial approach.
Kaushal A, Wani WY, Anand R, Gill KD. Kaushal A, et al. Am J Alzheimers Dis Other Demen. 2013 Jun;28(4):318-26. doi: 10.1177/1533317513488914. Epub 2013 May 17. Am J Alzheimers Dis Other Demen. 2013. PMID: 23687185 Review.
A complete animal model of AD should imitate all the cognitive, behavioral, and neuropathological features of the disease. Partial models are currently in use, which only mimic specific and not all of the components of AD pathology. Currently the transgenic animals are the
A complete animal model of AD should imitate all the cognitive, behavioral, and neuropathological features of the disease. Partial mo
Apolipoprotein E levels in the cerebrospinal fluid of north Indian patients with Alzheimer's disease.
Kandimalla RJ, Wani WY, Anand R, Kaushal A, Prabhakar S, Grover VK, Bharadwaj N, Jain K, Gill KD. Kandimalla RJ, et al. Am J Alzheimers Dis Other Demen. 2013 May;28(3):258-62. doi: 10.1177/1533317513481097. Am J Alzheimers Dis Other Demen. 2013. PMID: 23612909
Apolipoprotein E (ApoE) gene plays a pivotal role in risk and age of onset of AD. Although it is broadly accepted that ApoE genotype is linked to the pathogenesis of AD, there are still controversial results regarding the association of ApoE levels in cerebrospinal fluid ( …
Apolipoprotein E (ApoE) gene plays a pivotal role in risk and age of onset of AD. Although it is broadly accepted that ApoE genotype …
CSF p-Tau levels in the prediction of Alzheimer's disease.
Kandimalla RJ, Prabhakar S, Wani WY, Kaushal A, Gupta N, Sharma DR, Grover VK, Bhardwaj N, Jain K, Gill KD. Kandimalla RJ, et al. Biol Open. 2013 Sep 4;2(11):1119-24. doi: 10.1242/bio.20135447. eCollection 2013. Biol Open. 2013. PMID: 24244848 Free PMC article.
There is an urgent need to develop a reliable biomarker for the diagnosis of AD. Cerebrospinal fluid (CSF) is surrounding the brain and reflects the major neuropathological features in the AD brain. ...Therefore elevated levels of p-Tau in AD can be exploited as a p …
There is an urgent need to develop a reliable biomarker for the diagnosis of AD. Cerebrospinal fluid (CSF) is surrounding the brain a …
Road to Alzheimer's disease: the pathomechanism underlying.
Anand R, Kaushal A, Wani WY, Gill KD. Anand R, et al. Pathobiology. 2012;79(2):55-71. doi: 10.1159/000332218. Epub 2011 Dec 28. Pathobiology. 2012. PMID: 22205086 Review.
Alzheimer's disease (AD), the most common cause of dementia, results from the interplay of various deregulated mechanisms triggering a complex pathophysiology. ...The present article attempts to review the current literature regarding AD pathophysiology and proposes a
Alzheimer's disease (AD), the most common cause of dementia, results from the interplay of various deregulated mechanisms triggering a
Okadaic Acid and Hypoxia Induced Dementia Model of Alzheimer's Type in Rats.
Kaushal A, Wani WY, Bal A, Gill KD, Kaur J. Kaushal A, et al. Neurotox Res. 2019 Apr;35(3):621-634. doi: 10.1007/s12640-019-0005-9. Epub 2019 Feb 7. Neurotox Res. 2019. PMID: 30729451
Intracerebroventricular (ICV) injection of okadaic acid (OKA), a protein phosphatase 2A (PP2A) inhibitor, in rats causes neurotoxicity associated with neurofibrillary degeneration. ...We aimed at combining two different treatments and hence producing a better animal …
Intracerebroventricular (ICV) injection of okadaic acid (OKA), a protein phosphatase 2A (PP2A) inhibitor, in rats causes neurotoxicit …
Effect of acute aluminum phosphide exposure on rats: a biochemical and histological correlation.
Anand R, Kumari P, Kaushal A, Bal A, Wani WY, Sunkaria A, Dua R, Singh S, Bhalla A, Gill KD. Anand R, et al. Toxicol Lett. 2012 Nov 23;215(1):62-9. doi: 10.1016/j.toxlet.2012.09.020. Epub 2012 Oct 2. Toxicol Lett. 2012. PMID: 23041170
Aluminum phosphide (AlP), a widely used fumigant and rodenticide leads to high mortality if ingested. Its toxicity is due to phosphine liberated when it comes in contact with moisture. ...There was also a marked reduction in the cytochrome-c immunostaining compared …
Aluminum phosphide (AlP), a widely used fumigant and rodenticide leads to high mortality if ingested. Its toxicity is due to phosphin …
Cell cycle activation in p21 dependent pathway: An alternative mechanism of organophosphate induced dopaminergic neurodegeneration.
Wani WY, Kandimalla RJL, Sharma DR, Kaushal A, Ruban A, Sunkaria A, Vallamkondu J, Chiarugi A, Reddy PH, Gill KD. Wani WY, et al. Biochim Biophys Acta Mol Basis Dis. 2017 Jul;1863(7):1858-1866. doi: 10.1016/j.bbadis.2016.05.014. Epub 2016 Jun 2. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27262357
Cell cycle analysis of dichlorvos exposed cells revealed a reduction of cells in the G(0)/G(1) phase of the cell cycle (25%), and a concomitant increase of cells in S phase (30%) and G2/M phase (43.3%) compared to control PC12 cells. Further, immunoblotting of cytoc …
Cell cycle analysis of dichlorvos exposed cells revealed a reduction of cells in the G(0)/G(1) phase of the cell cycle (25%), and …
Geographic Distribution of US Cohorts Used to Train Deep Learning Algorithms.
Kaushal A, Altman R, Langlotz C. Kaushal A, et al. JAMA. 2020 Sep 22;324(12):1212-1213. doi: 10.1001/jama.2020.12067. JAMA. 2020. PMID: 32960230 No abstract available.
Scalp Nerve Block: An Extended Use of Aerosol Box in COVID 19 Pandemic.
Mohammad H, Kaushal A, Agarwal A, Kausar S. Mohammad H, et al. Among authors: kaushal a. J Neurosurg Anesthesiol. 2020 Sep 1. doi: 10.1097/ANA.0000000000000729. Online ahead of print. J Neurosurg Anesthesiol. 2020. PMID: 32890055 No abstract available.
Diagnosis of scrub typhus: recent advancements and challenges.
Kala D, Gupta S, Nagraik R, Verma V, Thakur A, Kaushal A. Kala D, et al. Among authors: kaushal a. 3 Biotech. 2020 Sep;10(9):396. doi: 10.1007/s13205-020-02389-w. Epub 2020 Aug 18. 3 Biotech. 2020. PMID: 32834918 Free PMC article. Review.
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