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Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells.
Yamazaki R, Kusunoki N, Matsuzaki T, Hashimoto S, Kawai S. Yamazaki R, et al. Among authors: kawai s. FEBS Lett. 2002 Nov 6;531(2):278-84. doi: 10.1016/s0014-5793(02)03535-4. FEBS Lett. 2002. PMID: 12417326
Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis.
Kojima F, Naraba H, Miyamoto S, Beppu M, Aoki H, Kawai S. Kojima F, et al. Among authors: kawai s. Arthritis Res Ther. 2004;6(4):R355-65. doi: 10.1186/ar1195. Epub 2004 Jun 8. Arthritis Res Ther. 2004. PMID: 15225371 Free PMC article.
Prostaglandin E2 production in ovarian cancer cell lines is regulated by cyclooxygenase-1, not cyclooxygenase-2.
Kino Y, Kojima F, Kiguchi K, Igarashi R, Ishizuka B, Kawai S. Kino Y, et al. Among authors: kawai s. Prostaglandins Leukot Essent Fatty Acids. 2005 Aug;73(2):103-11. doi: 10.1016/j.plefa.2005.04.014. Prostaglandins Leukot Essent Fatty Acids. 2005. PMID: 15963707
Prostaglandin E synthase in the pathophysiology of arthritis.
Kojima F, Kato S, Kawai S. Kojima F, et al. Among authors: kawai s. Fundam Clin Pharmacol. 2005 Jun;19(3):255-61. doi: 10.1111/j.1472-8206.2005.00316.x. Fundam Clin Pharmacol. 2005. PMID: 15910650 Review.
[Preventing effects of COX-2 inhibitors on rheumatoid joint destruction].
Kawai S, Kusunoki N, Kojima F. Kawai S, et al. Clin Calcium. 2003 Jun;13(6):739-45. Clin Calcium. 2003. PMID: 15775145 Japanese.
Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts.
Kusunoki N, Yamazaki R, Kitasato H, Beppu M, Aoki H, Kawai S. Kusunoki N, et al. Among authors: kawai s. BMC Pharmacol. 2004 Feb 17;4:2. doi: 10.1186/1471-2210-4-2. BMC Pharmacol. 2004. PMID: 15040811 Free PMC article.
Current drug therapy for rheumatoid arthritis.
Kawai S. Kawai S. J Orthop Sci. 2003;8(2):259-63. doi: 10.1007/s007760300045. J Orthop Sci. 2003. PMID: 12665969
Aspirin and sodium salicylate inhibit proliferation and induce apoptosis in rheumatoid synovial cells.
Yamazaki R, Kusunoki N, Matsuzaki T, Hashimoto S, Kawai S. Yamazaki R, et al. Among authors: kawai s. J Pharm Pharmacol. 2002 Dec;54(12):1675-9. doi: 10.1211/002235702261. J Pharm Pharmacol. 2002. PMID: 12542898
[Recent development of selective cyclooxygenase-2 inhibitors].
Kawai S. Kawai S. Nihon Rinsho. 2002 Dec;60(12):2370-7. Nihon Rinsho. 2002. PMID: 12510364 Review. Japanese.
Induction of apoptosis in rheumatoid synovial fibroblasts by celecoxib, but not by other selective cyclooxygenase 2 inhibitors.
Kusunoki N, Yamazaki R, Kawai S. Kusunoki N, et al. Among authors: kawai s. Arthritis Rheum. 2002 Dec;46(12):3159-67. doi: 10.1002/art.10692. Arthritis Rheum. 2002. PMID: 12483719
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