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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors.
Kawai T, Akira S. Kawai T, et al. Nat Immunol. 2010 May;11(5):373-84. doi: 10.1038/ni.1863. Epub 2010 Apr 20. Nat Immunol. 2010. PMID: 20404851 Review.
IPS-1 differentially induces TRAIL, BCL2, BIRC3 and PRKCE in type I interferons-dependent and -independent anticancer activity.
Kumar S, Ingle H, Mishra S, Mahla RS, Kumar A, Kawai T, Akira S, Takaoka A, Raut AA, Kumar H. Kumar S, et al. Among authors: kawai t. Cell Death Dis. 2015 May 7;6(5):e1758. doi: 10.1038/cddis.2015.122. Cell Death Dis. 2015. PMID: 25950488 Free PMC article.
TLR signaling.
Kawai T, Akira S. Kawai T, et al. Cell Death Differ. 2006 May;13(5):816-25. doi: 10.1038/sj.cdd.4401850. Cell Death Differ. 2006. PMID: 16410796 Review.
Discrimination of bacterial lipoproteins by Toll-like receptor 6.
Takeuchi O, Kawai T, Mühlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S. Takeuchi O, et al. Among authors: kawai t. Int Immunol. 2001 Jul;13(7):933-40. doi: 10.1093/intimm/13.7.933. Int Immunol. 2001. PMID: 11431423
A Toll-like receptor recognizes bacterial DNA.
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S. Hemmi H, et al. Among authors: kawai t. Nature. 2000 Dec 7;408(6813):740-5. doi: 10.1038/35047123. Nature. 2000. PMID: 11130078
CpG DNA induces a strong T-helper-1-like inflammatory response. Accumulating evidence has revealed the therapeutic potential of CpG DNA as adjuvants for vaccination strategies for cancer, allergy and infectious diseases. ...The in vivo CpG-DNA-mediated T-helper type …
CpG DNA induces a strong T-helper-1-like inflammatory response. Accumulating evidence has revealed the therapeutic potential of CpG D …
Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways.
Sato S, Nomura F, Kawai T, Takeuchi O, Mühlradt PF, Takeda K, Akira S. Sato S, et al. Among authors: kawai t. J Immunol. 2000 Dec 15;165(12):7096-101. doi: 10.4049/jimmunol.165.12.7096. J Immunol. 2000. PMID: 11120839
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S. Takeuchi O, et al. Among authors: kawai t. Immunity. 1999 Oct;11(4):443-51. doi: 10.1016/s1074-7613(00)80119-3. Immunity. 1999. PMID: 10549626
Human mannan-binding lectin inhibits the infection of influenza A virus without complement.
Kase T, Suzuki Y, Kawai T, Sakamoto T, Ohtani K, Eda S, Maeda A, Okuno Y, Kurimura T, Wakamiya N. Kase T, et al. Among authors: kawai t. Immunology. 1999 Jul;97(3):385-92. doi: 10.1046/j.1365-2567.1999.00781.x. Immunology. 1999. PMID: 10447758 Free PMC article.
Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase.
Kuwahara K, Kawai T, Mitsuyoshi S, Matsuo Y, Kikuchi H, Imajoh-Ohmi S, Hashimoto E, Inui S, Cooper MD, Sakaguchi N. Kuwahara K, et al. Among authors: kawai t. Int Immunol. 1996 Aug;8(8):1273-85. doi: 10.1093/intimm/8.8.1273. Int Immunol. 1996. PMID: 8918697
Antigen direction of specific T-cell clones into gingival tissues.
Kawai T, Shimauchi H, Eastcott JW, Smith DJ, Taubman MA. Kawai T, et al. Immunology. 1998 Jan;93(1):11-9. doi: 10.1046/j.1365-2567.1998.00408.x. Immunology. 1998. PMID: 9536113 Free PMC article.
This study was performed to investigate T-cell traffic to periodontal tissues during infection with a periodontal pathogen Actinobacillus actinomycetemcomitans (Aa). ...Binding of both T-cell clones to rat endothelial cells in vitro was blocked by antibody to VLA-4. …
This study was performed to investigate T-cell traffic to periodontal tissues during infection with a periodontal pathogen Actinobaci …
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