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Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells.
Nanbo A, Kawanishi E, Yoshida R, Yoshiyama H. Nanbo A, et al. Among authors: kawanishi e. J Virol. 2013 Sep;87(18):10334-47. doi: 10.1128/JVI.01310-13. Epub 2013 Jul 17. J Virol. 2013. PMID: 23864627 Free PMC article.
Caspase-dependent cleavage regulates protein levels of Epstein-Barr virus-derived latent membrane protein 1.
Togi S, Hatano Y, Muromoto R, Kawanishi E, Ikeda O, Hirashima K, Kon S, Kitai Y, Yasui T, Oritani K, Matsuda T. Togi S, et al. Among authors: kawanishi e. FEBS Lett. 2016 Mar;590(6):808-18. doi: 10.1002/1873-3468.12119. Epub 2016 Mar 4. FEBS Lett. 2016. PMID: 26921582 Free article.
Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety.
Koizumi Y, Tanaka Y, Matsumura T, Kadoh Y, Miyoshi H, Hongu M, Takedomi K, Kotera J, Sasaki T, Taniguchi H, Watanabe Y, Takakuwa M, Kojima K, Baba N, Nakamura I, Kawanishi E. Koizumi Y, et al. Among authors: kawanishi e. Bioorg Med Chem. 2019 Aug 1;27(15):3440-3450. doi: 10.1016/j.bmc.2019.06.021. Epub 2019 Jun 19. Bioorg Med Chem. 2019. PMID: 31235264
Synthetic Method for 2'-Amino-LNA Bearing Any of the Four Nucleobases via a Transglycosylation Reaction.
Sawamoto H, Arai Y, Yamakoshi S, Obika S, Kawanishi E. Sawamoto H, et al. Among authors: kawanishi e. Org Lett. 2018 Apr 6;20(7):1928-1931. doi: 10.1021/acs.orglett.8b00476. Epub 2018 Mar 12. Org Lett. 2018. PMID: 29528240
Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor.
Kadoh Y, Miyoshi H, Matsumura T, Tanaka Y, Hongu M, Kimura M, Takedomi K, Omori K, Kotera J, Sasaki T, Kobayashi T, Taniguchi H, Watanabe Y, Kojima K, Sakamoto T, Himiyama T, Kawanishi E. Kadoh Y, et al. Among authors: kawanishi e. Chem Pharm Bull (Tokyo). 2018;66(3):243-250. doi: 10.1248/cpb.c17-00783. Chem Pharm Bull (Tokyo). 2018. PMID: 29491258 Free article.
Baseline feature of a randomized trial assessing the effects of disease management programs for the prevention of recurrent ischemic stroke.
Fukuoka Y, Hosomi N, Hyakuta T, Omori T, Ito Y, Uemura J, Kimura K, Matsumoto M, Moriyama M; DMP Stroke Trial Investigators. Fukuoka Y, et al. J Stroke Cerebrovasc Dis. 2015 Mar;24(3):610-7. doi: 10.1016/j.jstrokecerebrovasdis.2014.10.007. Epub 2015 Jan 6. J Stroke Cerebrovasc Dis. 2015. PMID: 25576351 Free article. Clinical Trial.
Phosphodiesterase 10A PET radioligand development program: from pig to human.
Plisson C, Weinzimmer D, Jakobsen S, Natesan S, Salinas C, Lin SF, Labaree D, Zheng MQ, Nabulsi N, Marques TR, Kapur S, Kawanishi E, Saijo T, Gunn RN, Carson RE, Rabiner EA. Plisson C, et al. Among authors: kawanishi e. J Nucl Med. 2014 Apr;55(4):595-601. doi: 10.2967/jnumed.113.131409. Epub 2014 Mar 10. J Nucl Med. 2014. PMID: 24614221 Free article.
Synthesis and biological evaluation of thiophene-C-glucosides as sodium-dependent glucose cotransporter 2 inhibitors.
Sakamaki S, Kawanishi E, Koga Y, Yamamoto Y, Kuriyama C, Matsushita Y, Ueta K, Nomura S. Sakamaki S, et al. Among authors: kawanishi e. Chem Pharm Bull (Tokyo). 2013;61(10):1037-43. doi: 10.1248/cpb.c13-00407. Chem Pharm Bull (Tokyo). 2013. PMID: 24088695 Free article.
N-Glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors.
Yamamoto Y, Kawanishi E, Koga Y, Sakamaki S, Sakamoto T, Ueta K, Matsushita Y, Kuriyama C, Tsuda-Tsukimoto M, Nomura S. Yamamoto Y, et al. Among authors: kawanishi e. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5641-5. doi: 10.1016/j.bmcl.2013.08.042. Epub 2013 Aug 17. Bioorg Med Chem Lett. 2013. PMID: 23999047
C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors.
Koga Y, Sakamaki S, Hongu M, Kawanishi E, Sakamoto T, Yamamoto Y, Kimata H, Nakayama K, Kuriyama C, Matsushita Y, Ueta K, Tsuda-Tsukimoto M, Nomura S. Koga Y, et al. Among authors: kawanishi e. Bioorg Med Chem. 2013 Sep 1;21(17):5561-72. doi: 10.1016/j.bmc.2013.05.048. Epub 2013 Jun 4. Bioorg Med Chem. 2013. PMID: 23809172
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