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PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.
Kawase T, Ohki R, Shibata T, Tsutsumi S, Kamimura N, Inazawa J, Ohta T, Ichikawa H, Aburatani H, Tashiro F, Taya Y. Kawase T, et al. Cell. 2009 Feb 6;136(3):535-50. doi: 10.1016/j.cell.2008.12.002. Cell. 2009. PMID: 19203586 Free article.
PHLDA1, another PHLDA family protein that inhibits Akt.
Chen Y, Takikawa M, Tsutsumi S, Yamaguchi Y, Okabe A, Shimada M, Kawase T, Sada A, Ezawa I, Takano Y, Nagata K, Suzuki Y, Semba K, Aburatani H, Ohki R. Chen Y, et al. Among authors: kawase t. Cancer Sci. 2018 Nov;109(11):3532-3542. doi: 10.1111/cas.13796. Epub 2018 Oct 13. Cancer Sci. 2018. PMID: 30207029 Free PMC article.
PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.
Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, Tycko B, Tsukada T, Kanai Y, Sumi S, Namiki H, Taya Y, Shibata T, Nakagama H. Ohki R, et al. Among authors: kawase t. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2404-13. doi: 10.1073/pnas.1319962111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912192 Free PMC article.
1,228 results