Kay DG - Search Results

1

In vivo mutational analysis of the N-terminal region of HIV-1 Nef reveals critical motifs for the development of an AIDS-like disease in CD4C/HIV transgenic mice.

Hanna Z, Priceputu E, Kay DG, Poudrier J, Chrobak P, Jolicoeur P. Hanna Z, et al. Among authors: kay dg. Virology. 2004 Oct 1;327(2):273-86. doi: 10.1016/j.virol.2004.06.028. Virology. 2004. PMID: 15351215

2

Overexpression of Notch1 ectodomain in myeloid cells induces vascular malformations through a paracrine pathway.

Li X, Calvo E, Cool M, Chrobak P, Kay DG, Jolicoeur P. Li X, et al. Among authors: kay dg. Am J Pathol. 2007 Jan;170(1):399-415. doi: 10.2353/ajpath.2007.060351. Am J Pathol. 2007. PMID: 17200211 Free PMC article.

3

Expression of constitutively active Notch1 in male genital tracts results in ectopic growth and blockage of efferent ducts, epididymal hyperplasia and sterility.

Lupien M, Diévart A, Morales CR, Hermo L, Calvo E, Kay DG, Hu C, Jolicoeur P. Lupien M, et al. Among authors: kay dg. Dev Biol. 2006 Dec 15;300(2):497-511. doi: 10.1016/j.ydbio.2006.09.010. Epub 2006 Sep 14. Dev Biol. 2006. PMID: 17046738

4

Structurally distinct ligand-binding or ligand-independent Notch1 mutants are leukemogenic but affect thymocyte development, apoptosis, and metastasis differently.

Priceputu E, Bouallaga I, Zhang Y, Li X, Chrobak P, Hanna ZS, Poudrier J, Kay DG, Jolicoeur P. Priceputu E, et al. Among authors: kay dg. J Immunol. 2006 Aug 15;177(4):2153-66. doi: 10.4049/jimmunol.177.4.2153. J Immunol. 2006. PMID: 16887975

5

The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleukin-1beta-converting enzyme-deficient or Bcl2-expressing transgenic mice.

Priceputu E, Rodrigue I, Chrobak P, Poudrier J, Mak TW, Hanna Z, Hu C, Kay DG, Jolicoeur P. Priceputu E, et al. Among authors: kay dg. J Virol. 2005 May;79(10):6377-91. doi: 10.1128/JVI.79.10.6377-6391.2005. J Virol. 2005. PMID: 15858021 Free PMC article.

6

CD4+ T cells from CD4C/HIVNef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease.

Weng X, Priceputu E, Chrobak P, Poudrier J, Kay DG, Hanna Z, Mak TW, Jolicoeur P. Weng X, et al. Among authors: kay dg. J Virol. 2004 May;78(10):5244-57. doi: 10.1128/jvi.78.10.5244-5257.2004. J Virol. 2004. PMID: 15113906 Free PMC article.

7

Protection against murine leukemia virus-induced spongiform myeloencephalopathy in mice overexpressing Bcl-2 but not in mice deficient for interleukin-6, inducible nitric oxide synthetase, ICE, Fas, Fas ligand, or TNF-R1 genes.

Jolicoeur P, Hu C, Mak TW, Martinou JC, Kay DG. Jolicoeur P, et al. Among authors: kay dg. J Virol. 2003 Dec;77(24):13161-70. doi: 10.1128/jvi.77.24.13161-13170.2003. J Virol. 2003. PMID: 14645573 Free PMC article.

8

Oligodendrocyte-specific expression of human immunodeficiency virus type 1 Nef in transgenic mice leads to vacuolar myelopathy and alters oligodendrocyte phenotype in vitro.

Radja F, Kay DG, Albrecht S, Jolicoeur P. Radja F, et al. Among authors: kay dg. J Virol. 2003 Nov;77(21):11745-53. doi: 10.1128/jvi.77.21.11745-11753.2003. J Virol. 2003. PMID: 14557659 Free PMC article.

9

The AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with accumulation of immature CD11bHi dendritic cells.

Poudrier J, Weng X, Kay DG, Hanna Z, Jolicoeur P. Poudrier J, et al. Among authors: kay dg. J Virol. 2003 Nov;77(21):11733-44. doi: 10.1128/jvi.77.21.11733-11744.2003. J Virol. 2003. PMID: 14557658 Free PMC article.

10

Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 nef in cells of the immune system.

Kay DG, Yue P, Hanna Z, Jothy S, Tremblay E, Jolicoeur P. Kay DG, et al. Am J Pathol. 2002 Jul;161(1):321-35. doi: 10.1016/S0002-9440(10)64184-3. Am J Pathol. 2002. PMID: 12107117 Free PMC article.

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