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Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities.
Ji RR, de Silva H, Jin Y, Bruccoleri RE, Cao J, He A, Huang W, Kayne PS, Neuhaus IM, Ott KH, Penhallow B, Cockett MI, Neubauer MG, Siemers NO, Ross-Macdonald P. Ji RR, et al. Among authors: kayne ps. PLoS Comput Biol. 2009 Sep;5(9):e1000512. doi: 10.1371/journal.pcbi.1000512. Epub 2009 Sep 18. PLoS Comput Biol. 2009. PMID: 19763178 Free PMC article.
Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer.
Manjarrez-Orduño N, Menard LC, Kansal S, Fischer P, Kakrecha B, Jiang C, Cunningham M, Greenawalt D, Patel V, Yang M, Golhar R, Carman JA, Lezhnin S, Dai H, Kayne PS, Suchard SJ, Bernstein SH, Nadler SG. Manjarrez-Orduño N, et al. Among authors: kayne ps. Front Immunol. 2018 Aug 3;9:1613. doi: 10.3389/fimmu.2018.01613. eCollection 2018. Front Immunol. 2018. PMID: 30123214 Free PMC article.
A novel oral formulation of the melanocortin-1 receptor agonist PL8177 resolves inflammation in preclinical studies of inflammatory bowel disease and is gut restricted in rats, dogs, and humans.
Dodd J, Jordan R, Makhlina M, Barnett K, Roffel A, Spana C, Obr A, Dhingra P, Kayne PS. Dodd J, et al. Among authors: kayne ps. Front Immunol. 2023 Feb 20;14:1083333. doi: 10.3389/fimmu.2023.1083333. eCollection 2023. Front Immunol. 2023. PMID: 36891301 Free PMC article.
18 results