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The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance.
Kimura I, Kosugi Y, Wu J, Zahradnik J, Yamasoba D, Butlertanaka EP, Tanaka YL, Uriu K, Liu Y, Morizako N, Shirakawa K, Kazuma Y, Nomura R, Horisawa Y, Tokunaga K, Ueno T, Takaori-Kondo A, Schreiber G, Arase H; Genotype to Phenotype Japan (G2P-Japan) Consortium; Motozono C, Saito A, Nakagawa S, Sato K. Kimura I, et al. Among authors: kazuma y. Cell Rep. 2022 Jan 11;38(2):110218. doi: 10.1016/j.celrep.2021.110218. Epub 2021 Dec 18. Cell Rep. 2022. PMID: 34968415 Free PMC article.
Classical NF-κB pathway is responsible for APOBEC3B expression in cancer cells.
Maruyama W, Shirakawa K, Matsui H, Matsumoto T, Yamazaki H, Sarca AD, Kazuma Y, Kobayashi M, Shindo K, Takaori-Kondo A. Maruyama W, et al. Among authors: kazuma y. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1466-71. doi: 10.1016/j.bbrc.2016.08.148. Epub 2016 Aug 27. Biochem Biophys Res Commun. 2016. PMID: 27577680 Free article.
Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation.
Matsumoto T, Shirakawa K, Yokoyama M, Fukuda H, Sarca AD, Koyabu S, Yamazaki H, Kazuma Y, Matsui H, Maruyama W, Nagata K, Tanabe F, Kobayashi M, Shindo K, Morishita R, Sato H, Takaori-Kondo A. Matsumoto T, et al. Among authors: kazuma y. Sci Rep. 2019 Jun 5;9(1):8307. doi: 10.1038/s41598-019-44407-9. Sci Rep. 2019. PMID: 31165764 Free PMC article.
Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator.
Takei H, Fukuda H, Pan G, Yamazaki H, Matsumoto T, Kazuma Y, Fujii M, Nakayama S, Kobayashi IS, Shindo K, Yamashita R, Shirakawa K, Takaori-Kondo A, Kobayashi SS. Takei H, et al. Among authors: kazuma y. Int J Hematol. 2020 Sep;112(3):395-408. doi: 10.1007/s12185-020-02904-y. Epub 2020 Jun 12. Int J Hematol. 2020. PMID: 32533515 Free PMC article.
CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model.
Matsui H, Shirakawa K, Konishi Y, Hirabayashi S, Sarca AD, Fukuda H, Nomura R, Stanford E, Horisawa Y, Kazuma Y, Matsumoto T, Yamazaki H, Murakawa Y, Battivelli E, Verdin E, Koyanagi Y, Takaori-Kondo A. Matsui H, et al. Among authors: kazuma y. J Virol. 2021 Mar 25;95(8):e02394-20. doi: 10.1128/JVI.02394-20. Epub 2021 Jan 27. J Virol. 2021. PMID: 33504604 Free PMC article.
APOBEC3B is preferentially expressed at the G2/M phase of cell cycle.
Hirabayashi S, Shirakawa K, Horisawa Y, Matsumoto T, Matsui H, Yamazaki H, Sarca AD, Kazuma Y, Nomura R, Konishi Y, Takeuchi S, Stanford E, Kawaji H, Murakawa Y, Takaori-Kondo A. Hirabayashi S, et al. Among authors: kazuma y. Biochem Biophys Res Commun. 2021 Mar 26;546:178-184. doi: 10.1016/j.bbrc.2021.02.008. Epub 2021 Feb 13. Biochem Biophys Res Commun. 2021. PMID: 33592502 Free article.
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
Mlcochova P, Kemp SA, Dhar MS, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S, Ponnusamy K, Radhakrishnan VS, Abdullahi A, Charles O, Chattopadhyay P, Devi P, Caputo D, Peacock T, Wattal C, Goel N, Satwik A, Vaishya R, Agarwal M; Indian SARS-CoV-2 Genomics Consortium (INSACOG); Genotype to Phenotype Japan (G2P-Japan) Consortium; CITIID-NIHR BioResource COVID-19 Collaboration; Mavousian A, Lee JH, Bassi J, Silacci-Fegni C, Saliba C, Pinto D, Irie T, Yoshida I, Hamilton WL, Sato K, Bhatt S, Flaxman S, James LC, Corti D, Piccoli L, Barclay WS, Rakshit P, Agrawal A, Gupta RK. Mlcochova P, et al. Nature. 2021 Nov;599(7883):114-119. doi: 10.1038/s41586-021-03944-y. Epub 2021 Sep 6. Nature. 2021. PMID: 34488225 Free PMC article.
29 results