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Cyclic peptides incorporating 4-carboxyphenylalanine and phosphotyrosine are potent inhibitors of pp60(c-)(src).
Wang W, Ramdas L, Sun G, Ke S, Obeyesekere NU, Budde RJ, McMurray JS. Wang W, et al. Among authors: ke s. Biochemistry. 2000 May 2;39(17):5221-8. doi: 10.1021/bi992994f. Biochemistry. 2000. PMID: 10819990
We have been employing cyclic decapeptides to identify the determinants for substrate binding and phosphorylation to develop inhibitors competitive with protein substrates of Src. A structure-activity study [McMurray, J. S., Budde, R. J. A., Ke, S., Obeyeseke …
We have been employing cyclic decapeptides to identify the determinants for substrate binding and phosphorylation to develop inhibitors comp …
1,038 results