Kedl RM - Search Results

1

The immune response modifier and Toll-like receptor 7 agonist S-27609 selectively induces IL-12 and TNF-alpha production in CD11c+CD11b+CD8- dendritic cells.

Doxsee CL, Riter TR, Reiter MJ, Gibson SJ, Vasilakos JP, Kedl RM. Doxsee CL, et al. Among authors: kedl rm. J Immunol. 2003 Aug 1;171(3):1156-63. doi: 10.4049/jimmunol.171.3.1156. J Immunol. 2003. PMID: 12874201

2

Qualitative differences between naive and memory T cells make a major contribution to the more rapid and efficient memory CD8+ T cell response.

Kedl RM, Mescher MF. Kedl RM, et al. J Immunol. 1998 Jul 15;161(2):674-83. J Immunol. 1998. PMID: 9670942

3

Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells.

Curtsinger JM, Schmidt CS, Mondino A, Lins DC, Kedl RM, Jenkins MK, Mescher MF. Curtsinger JM, et al. Among authors: kedl rm. J Immunol. 1999 Mar 15;162(6):3256-62. J Immunol. 1999. PMID: 10092777

4

CD8+ T cells become nonresponsive (anergic) following activation in the presence of costimulation.

Deeths MJ, Kedl RM, Mescher MF. Deeths MJ, et al. Among authors: kedl rm. J Immunol. 1999 Jul 1;163(1):102-10. J Immunol. 1999. PMID: 10384105

5

Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod.

Gibson SJ, Lindh JM, Riter TR, Gleason RM, Rogers LM, Fuller AE, Oesterich JL, Gorden KB, Qiu X, McKane SW, Noelle RJ, Miller RL, Kedl RM, Fitzgerald-Bocarsly P, Tomai MA, Vasilakos JP. Gibson SJ, et al. Among authors: kedl rm. Cell Immunol. 2002 Jul-Aug;218(1-2):74-86. doi: 10.1016/s0008-8749(02)00517-8. Cell Immunol. 2002. PMID: 12470615

6

Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN.

Ahonen CL, Doxsee CL, McGurran SM, Riter TR, Wade WF, Barth RJ, Vasilakos JP, Noelle RJ, Kedl RM. Ahonen CL, et al. Among authors: kedl rm. J Exp Med. 2004 Mar 15;199(6):775-84. doi: 10.1084/jem.20031591. Epub 2004 Mar 8. J Exp Med. 2004. PMID: 15007094 Free PMC article.

7

Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.

Gorden KB, Gorski KS, Gibson SJ, Kedl RM, Kieper WC, Qiu X, Tomai MA, Alkan SS, Vasilakos JP. Gorden KB, et al. Among authors: kedl rm. J Immunol. 2005 Feb 1;174(3):1259-68. doi: 10.4049/jimmunol.174.3.1259. J Immunol. 2005. PMID: 15661881

8

Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.

Wille-Reece U, Wu CY, Flynn BJ, Kedl RM, Seder RA. Wille-Reece U, et al. Among authors: kedl rm. J Immunol. 2005 Jun 15;174(12):7676-83. doi: 10.4049/jimmunol.174.12.7676. J Immunol. 2005. PMID: 15944268

9

A modified tyrosinase-related protein 2 epitope generates high-affinity tumor-specific T cells but does not mediate therapeutic efficacy in an intradermal tumor model.

McWilliams JA, McGurran SM, Dow SW, Slansky JE, Kedl RM. McWilliams JA, et al. Among authors: kedl rm. J Immunol. 2006 Jul 1;177(1):155-61. doi: 10.4049/jimmunol.177.1.155. J Immunol. 2006. PMID: 16785510

10

Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo.

Sanchez PJ, McWilliams JA, Haluszczak C, Yagita H, Kedl RM. Sanchez PJ, et al. Among authors: kedl rm. J Immunol. 2007 Feb 1;178(3):1564-72. doi: 10.4049/jimmunol.178.3.1564. J Immunol. 2007. PMID: 17237405

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