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Flavin-containing monooxygenase S-oxygenation of a series of thioureas and thiones.
Henderson MC, Siddens LK, Krueger SK, Stevens JF, Kedzie K, Fang WK, Heidelbaugh T, Nguyen P, Chow K, Garst M, Gil D, Williams DE. Henderson MC, et al. Among authors: kedzie k. Toxicol Appl Pharmacol. 2014 Jul 15;278(2):91-9. doi: 10.1016/j.taap.2014.04.002. Epub 2014 Apr 12. Toxicol Appl Pharmacol. 2014. PMID: 24727368 Free PMC article.
Replacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compounds.
Woodward DF, Krauss AH, Chen J, Gil DW, Kedzie KM, Protzman CE, Shi L, Chen R, Krauss HA, Bogardus A, Dinh HT, Wheeler LA, Andrews SW, Burk RM, Gac T, Roof MB, Garst ME, Kaplan LJ, Sachs G, Pierce KL, Regan JW, Ross RA, Chan MF. Woodward DF, et al. Among authors: kedzie km. Br J Pharmacol. 2000 Aug;130(8):1933-43. doi: 10.1038/sj.bjp.0703462. Br J Pharmacol. 2000. PMID: 10952685 Free PMC article.
Pharmacological characterization of a novel antiglaucoma agent, Bimatoprost (AGN 192024).
Woodward DF, Krauss AH, Chen J, Liang Y, Li C, Protzman CE, Bogardus A, Chen R, Kedzie KM, Krauss HA, Gil DW, Kharlamb A, Wheeler LA, Babusis D, Welty D, Tang-Liu DD, Cherukury M, Andrews SW, Burk RM, Garst ME. Woodward DF, et al. Among authors: kedzie km. J Pharmacol Exp Ther. 2003 May;305(2):772-85. doi: 10.1124/jpet.102.047837. Epub 2003 Jan 24. J Pharmacol Exp Ther. 2003. PMID: 12606640
The pharmacology of bimatoprost (Lumigan).
Woodward DF, Krauss AH, Chen J, Lai RK, Spada CS, Burk RM, Andrews SW, Shi L, Liang Y, Kedzie KM, Chen R, Gil DW, Kharlamb A, Archeampong A, Ling J, Madhu C, Ni J, Rix P, Usansky J, Usansky H, Weber A, Welty D, Yang W, Tang-Liu DD, Garst ME, Brar B, Wheeler LA, Kaplan LJ. Woodward DF, et al. Among authors: kedzie km. Surv Ophthalmol. 2001 May;45 Suppl 4:S337-45. doi: 10.1016/s0039-6257(01)00224-7. Surv Ophthalmol. 2001. PMID: 11434936 Review.
23 results