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Accelerating pharmaceutical structure-guided drug design: a successful model.

Keefe LJ, Stoll VS. Keefe LJ, et al. Drug Discov Today. 2019 Feb;24(2):377-381. doi: 10.1016/j.drudis.2018.11.008. Epub 2018 Nov 15. Drug Discov Today. 2019. PMID: 30448353

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Focusing, collimation and flux throughput at the IMCA-CAT bending-magnet beamline at the Advanced Photon Source.

Koshelev I, Huang R, Graber T, Meron M, Muir JL, Lavender W, Battaile K, Mulichak AM, Keefe LJ. Koshelev I, et al. Among authors: keefe lj. J Synchrotron Radiat. 2009 Sep;16(Pt 5):647-57. doi: 10.1107/S0909049509022353. Epub 2009 Jul 9. J Synchrotron Radiat. 2009. PMID: 19713639

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The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results.

Rosenbaum G, Alkire RW, Evans G, Rotella FJ, Lazarski K, Zhang RG, Ginell SL, Duke N, Naday I, Lazarz J, Molitsky MJ, Keefe L, Gonczy J, Rock L, Sanishvili R, Walsh MA, Westbrook E, Joachimiak A. Rosenbaum G, et al. J Synchrotron Radiat. 2006 Jan;13(Pt 1):30-45. doi: 10.1107/S0909049505036721. Epub 2005 Dec 22. J Synchrotron Radiat. 2006. PMID: 16371706 Free PMC article.

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Towards protein-crystal centering using second-harmonic generation (SHG) microscopy.

Kissick DJ, Dettmar CM, Becker M, Mulichak AM, Cherezov V, Ginell SL, Battaile KP, Keefe LJ, Fischetti RF, Simpson GJ. Kissick DJ, et al. Among authors: keefe lj. Acta Crystallogr D Biol Crystallogr. 2013 May;69(Pt 5):843-51. doi: 10.1107/S0907444913002746. Epub 2013 Apr 19. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23633594 Free PMC article.

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Crystallization and preliminary X-ray diffraction studies of the human adenovirus serotype 2 proteinase with peptide cofactor.

Keefe LJ, Ginell SL, Westbrook EM, Anderson CW. Keefe LJ, et al. Protein Sci. 1995 Aug;4(8):1658-60. doi: 10.1002/pro.5560040826. Protein Sci. 1995. PMID: 8520494 Free PMC article.

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Global radiation damage: temperature dependence, time dependence and how to outrun it.

Warkentin M, Hopkins JB, Badeau R, Mulichak AM, Keefe LJ, Thorne RE. Warkentin M, et al. Among authors: keefe lj. J Synchrotron Radiat. 2013 Jan;20(Pt 1):7-13. doi: 10.1107/S0909049512048303. Epub 2012 Nov 29. J Synchrotron Radiat. 2013. PMID: 23254651 Free PMC article.

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Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Edwards MR, Liu H, Shabman RS, Ginell GM, Luthra P, Ramanan P, Keefe LJ, Köllner B, Amarasinghe GK, Taylor DJ, Leung DW, Basler CF. Edwards MR, et al. Among authors: keefe lj. Cell Rep. 2018 Jul 24;24(4):861-872.e6. doi: 10.1016/j.celrep.2018.06.045. Cell Rep. 2018. PMID: 30044983 Free PMC article.

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Linear fitting of multi-threshold counting data with a pixel-array detector for spectral X-ray imaging.

Muir RD, Pogranichney NR, Muir JL, Sullivan SZ, Battaile KP, Mulichak AM, Toth SJ, Keefe LJ, Simpson GJ. Muir RD, et al. Among authors: keefe lj. J Synchrotron Radiat. 2014 Sep;21(Pt 5):1180-7. doi: 10.1107/S1600577514014167. Epub 2014 Aug 15. J Synchrotron Radiat. 2014. PMID: 25178010 Free PMC article.

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Global radiation damage at 300 and 260 K with dose rates approaching 1 MGy s⁻¹.

Warkentin M, Badeau R, Hopkins JB, Mulichak AM, Keefe LJ, Thorne RE. Warkentin M, et al. Among authors: keefe lj. Acta Crystallogr D Biol Crystallogr. 2012 Feb;68(Pt 2):124-33. doi: 10.1107/S0907444911052085. Epub 2012 Jan 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22281741 Free PMC article.

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Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.

Keefe LJ, Quirk S, Gittis A, Sondek J, Lattman EE. Keefe LJ, et al. Protein Sci. 1994 Mar;3(3):391-401. doi: 10.1002/pro.5560030303. Protein Sci. 1994. PMID: 8019410 Free PMC article.

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