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Response-driven combination therapy with conventional disease-modifying antirheumatic drugs can achieve high response rates in early rheumatoid arthritis with minimal glucocorticoid and nonsteroidal anti-inflammatory drug use.
Proudman SM, Keen HI, Stamp LK, Lee AT, Goldblatt F, Ayres OC, Rischmueller M, James MJ, Hill CL, Caughey GE, Cleland LG. Proudman SM, et al. Among authors: keen hi. Semin Arthritis Rheum. 2007 Oct;37(2):99-111. doi: 10.1016/j.semarthrit.2007.02.001. Epub 2007 Mar 27. Semin Arthritis Rheum. 2007. PMID: 17391739 Clinical Trial.
Assessing single joints in arthritis clinical trials.
Keen HI, Bingham CO 3rd, Bradley LA, Conaghan PG, Heald AE, Kaeley GS, Maksymowych WP, Moskowitz RW, Schumacher HR Jr, Woodworth TE, Mease PJ. Keen HI, et al. J Rheumatol. 2009 Sep;36(9):2092-6. doi: 10.3899/jrheum.090364. J Rheumatol. 2009. PMID: 19738219 Review.
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