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Immunotherapy in preneoplastic disease: targeting early procarcinogenic inflammatory changes that lead to immune suppression and tumor tolerance.
Keenan B, Jaffee EM. Keenan B, et al. Ann N Y Acad Sci. 2013 May;1284:12-6. doi: 10.1111/nyas.12076. Ann N Y Acad Sci. 2013. PMID: 23651188 Free PMC article. Review.
Whole cell vaccines--past progress and future strategies.
Keenan BP, Jaffee EM. Keenan BP, et al. Semin Oncol. 2012 Jun;39(3):276-86. doi: 10.1053/j.seminoncol.2012.02.007. Semin Oncol. 2012. PMID: 22595050 Free PMC article. Review.
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Keenan BP, Saenger Y, Kafrouni MI, Leubner A, Lauer P, Maitra A, Rucki AA, Gunderson AJ, Coussens LM, Brockstedt DG, Dubensky TW Jr, Hassan R, Armstrong TD, Jaffee EM. Keenan BP, et al. Gastroenterology. 2014 Jun;146(7):1784-94.e6. doi: 10.1053/j.gastro.2014.02.055. Epub 2014 Mar 6. Gastroenterology. 2014. PMID: 24607504 Free PMC article.
Tumor immunology: multidisciplinary science driving basic and clinical advances.
Keenan BP, Jaffee EM, Armstrong TD. Keenan BP, et al. Cancer Immunol Res. 2013 Jul;1(1):16-23. doi: 10.1158/2326-6066.CIR-13-0011. Cancer Immunol Res. 2013. PMID: 24409447 Free PMC article.
The key findings that emerged from this meeting included: (i) multiple immune checkpoints should be inhibited to increase effective T-cell therapy, (ii) successful adoptive T-cell therapy will rely on obtaining the proper T-cell phenotype, (iii) chimeric antigen receptors have sh …
The key findings that emerged from this meeting included: (i) multiple immune checkpoints should be inhibited to increase effective T-cell t …
True, True, Related? Autoimmune Polyglandular Syndrome Type II.
Keenan BP, Yalamanchi S, Hsu S, Norsworthy K, Brown TT. Keenan BP, et al. Am J Med. 2016 Jan;129(1):38-41. doi: 10.1016/j.amjmed.2015.08.032. Epub 2015 Oct 9. Am J Med. 2016. PMID: 26450169 No abstract available.
Efficient repair of DNA double-strand breaks in malignant cells with structural instability.
Cheng Y, Zhang Z, Keenan B, Roschke AV, Nakahara K, Aplan PD. Cheng Y, et al. Among authors: keenan b. Mutat Res. 2010 Jan 5;683(1-2):115-22. doi: 10.1016/j.mrfmmm.2009.10.016. Mutat Res. 2010. PMID: 19909760 Free PMC article.
Nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh class B cirrhosis: Safety and clinical outcomes in a retrospective case series.
Kambhampati S, Bauer KE, Bracci PM, Keenan BP, Behr SC, Gordan JD, Kelley RK. Kambhampati S, et al. Among authors: keenan bp. Cancer. 2019 Sep 15;125(18):3234-3241. doi: 10.1002/cncr.32206. Epub 2019 Jun 2. Cancer. 2019. PMID: 31154669
To the authors' knowledge, the safety and efficacy of nivolumab has not been established in patients with Child-Pugh class B (CPB) cirrhosis, a population with limited therapeutic options and a poor prognosis. ...
To the authors' knowledge, the safety and efficacy of nivolumab has not been established in patients with Child-Pugh class B (CPB) ci …
A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics.
Fialcowitz EJ, Brewer BY, Keenan BP, Wilson GM. Fialcowitz EJ, et al. Among authors: keenan bp. J Biol Chem. 2005 Jun 10;280(23):22406-17. doi: 10.1074/jbc.M500618200. Epub 2005 Apr 4. J Biol Chem. 2005. PMID: 15809297 Free PMC article.
The Complex Problem of Women Trainees in Academic Medicine.
Keenan B, Santhosh L, Thompson V, Harleman E. Keenan B, et al. J Hosp Med. 2019 Mar;14(3):186-188. doi: 10.12788/jhm.3131. J Hosp Med. 2019. PMID: 30811328 No abstract available.
Reply to: Weight Loss and Upper Airway Anatomy in Patients with Obstructive Sleep Apnea.
Schwab RJ, Keenan BT, Sarwer DB, Pack AI. Schwab RJ, et al. Among authors: keenan bt. Am J Respir Crit Care Med. 2020 Oct 19. doi: 10.1164/rccm.202009-3632LE. Online ahead of print. Am J Respir Crit Care Med. 2020. PMID: 33074713 No abstract available.
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