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The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy.
Norwood FL, Sutherland-Smith AJ, Keep NH, Kendrick-Jones J. Norwood FL, et al. Among authors: keep nh. Structure. 2000 May 15;8(5):481-91. doi: 10.1016/s0969-2126(00)00132-5. Structure. 2000. PMID: 10801490
Crystal structures of the human Dysferlin inner DysF domain.
Sula A, Cole AR, Yeats C, Orengo C, Keep NH. Sula A, et al. Among authors: keep nh. BMC Struct Biol. 2014 Jan 17;14:3. doi: 10.1186/1472-6807-14-3. BMC Struct Biol. 2014. PMID: 24438169 Free PMC article.
Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis.
Basavannacharya C, Moody PR, Munshi T, Cronin N, Keep NH, Bhakta S. Basavannacharya C, et al. Among authors: keep nh. Protein Cell. 2010 Nov;1(11):1011-22. doi: 10.1007/s13238-010-0132-9. Epub 2010 Dec 10. Protein Cell. 2010. PMID: 21153518 Free PMC article.
Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.
Patel P, Harris R, Geddes SM, Strehle EM, Watson JD, Bashir R, Bushby K, Driscoll PC, Keep NH. Patel P, et al. Among authors: keep nh. J Mol Biol. 2008 Jun 20;379(5):981-90. doi: 10.1016/j.jmb.2008.04.046. Epub 2008 Apr 26. J Mol Biol. 2008. PMID: 18495154
Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis.
Kennaway CK, Benesch JL, Gohlke U, Wang L, Robinson CV, Orlova EV, Saibil HR, Keep NH. Kennaway CK, et al. Among authors: keep nh. J Biol Chem. 2005 Sep 30;280(39):33419-25. doi: 10.1074/jbc.M504263200. Epub 2005 Jul 26. J Biol Chem. 2005. PMID: 16046399
The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes.
Cohen-Gonsaud M, Barthe P, Bagnéris C, Henderson B, Ward J, Roumestand C, Keep NH. Cohen-Gonsaud M, et al. Among authors: keep nh. Nat Struct Mol Biol. 2005 Mar;12(3):270-3. doi: 10.1038/nsmb905. Epub 2005 Feb 20. Nat Struct Mol Biol. 2005. PMID: 15723078
Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein.
Garavini H, Riento K, Phelan JP, McAlister MS, Ridley AJ, Keep NH. Garavini H, et al. Among authors: keep nh. Biochemistry. 2002 May 21;41(20):6303-10. doi: 10.1021/bi025651h. Biochemistry. 2002. PMID: 12009891
Resuscitation-promoting factors possess a lysozyme-like domain.
Cohen-Gonsaud M, Keep NH, Davies AP, Ward J, Henderson B, Labesse G. Cohen-Gonsaud M, et al. Among authors: keep nh. Trends Biochem Sci. 2004 Jan;29(1):7-10. doi: 10.1016/j.tibs.2003.10.009. Trends Biochem Sci. 2004. PMID: 14729326
Structure of the stationary phase survival protein YuiC from B.subtilis.
Quay DH, Cole AR, Cryar A, Thalassinos K, Williams MA, Bhakta S, Keep NH. Quay DH, et al. Among authors: keep nh. BMC Struct Biol. 2015 Jul 11;15:12. doi: 10.1186/s12900-015-0039-z. BMC Struct Biol. 2015. PMID: 26163297 Free PMC article.
The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation.
Edwards SD, Keep NH. Edwards SD, et al. Among authors: keep nh. Biochemistry. 2001 Jun 19;40(24):7061-8. doi: 10.1021/bi010419h. Biochemistry. 2001. PMID: 11401550
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