Keith B - Search Results

1

Hypoxia-inducible factors, stem cells, and cancer.

Keith B, Simon MC. Keith B, et al. Cell. 2007 May 4;129(3):465-72. doi: 10.1016/j.cell.2007.04.019. Cell. 2007. PMID: 17482542 Free PMC article. Review.

2

Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.

Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, Blair IA, Nissim I, Keith B, Simon MC. Ochocki JD, et al. Among authors: keith b. Cell Metab. 2018 Jun 5;27(6):1263-1280.e6. doi: 10.1016/j.cmet.2018.04.009. Epub 2018 May 10. Cell Metab. 2018. PMID: 29754953 Free PMC article.

3

Oxygen availability and metabolic adaptations.

Nakazawa MS, Keith B, Simon MC. Nakazawa MS, et al. Among authors: keith b. Nat Rev Cancer. 2016 Sep 23;16(10):663-73. doi: 10.1038/nrc.2016.84. Nat Rev Cancer. 2016. PMID: 27658636 Free PMC article. Review.

4

Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.

Mathew LK, Huangyang P, Mucaj V, Lee SS, Skuli N, Eisinger-Mathason TS, Biju K, Li B, Venneti S, Lal P, Lathia JD, Rich JN, Keith B, Simon MC. Mathew LK, et al. Among authors: keith b. Sci Signal. 2015 May 5;8(375):ra42. doi: 10.1126/scisignal.2005978. Sci Signal. 2015. PMID: 25943352 Free PMC article.

5

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress.

Young RM, Ackerman D, Quinn ZL, Mancuso A, Gruber M, Liu L, Giannoukos DN, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC. Young RM, et al. Among authors: keith b. Genes Dev. 2013 May 15;27(10):1115-31. doi: 10.1101/gad.198630.112. Genes Dev. 2013. PMID: 23699409 Free PMC article.

6

Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53.

Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL. Licciulli S, et al. Among authors: keith b. Cancer Res. 2013 Oct 1;73(19):5974-84. doi: 10.1158/0008-5472.CAN-13-1384. Epub 2013 Aug 13. Cancer Res. 2013. PMID: 23943799 Free PMC article.

7

Restricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal cell carcinomas enhances HIF2α activity.

Mathew LK, Lee SS, Skuli N, Rao S, Keith B, Nathanson KL, Lal P, Simon MC. Mathew LK, et al. Among authors: keith b. Cancer Discov. 2014 Jan;4(1):53-60. doi: 10.1158/2159-8290.CD-13-0291. Epub 2013 Nov 4. Cancer Discov. 2014. PMID: 24189146 Free PMC article.

8

Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18.

Hu B, Ren J, Luo Y, Keith B, Young RM, Scholler J, Zhao Y, June CH. Hu B, et al. Among authors: keith b. Cell Rep. 2017 Sep 26;20(13):3025-3033. doi: 10.1016/j.celrep.2017.09.002. Cell Rep. 2017. PMID: 28954221 Free PMC article.

9

Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis.

Skuli N, Liu L, Runge A, Wang T, Yuan L, Patel S, Iruela-Arispe L, Simon MC, Keith B. Skuli N, et al. Among authors: keith b. Blood. 2009 Jul 9;114(2):469-77. doi: 10.1182/blood-2008-12-193581. Epub 2009 May 13. Blood. 2009. PMID: 19439736 Free PMC article.

10

Hypoxia-induced energy stress regulates mRNA translation and cell growth.

Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC. Liu L, et al. Among authors: keith b. Mol Cell. 2006 Feb 17;21(4):521-31. doi: 10.1016/j.molcel.2006.01.010. Mol Cell. 2006. PMID: 16483933 Free PMC article.

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