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Decreased susceptibility to imipenem among penicillin-resistant Streptococcus pneumoniae.
Pikis A, Donkersloot JA, Akram S, Keith JM, Campos JM, Rodriguez WJ. Pikis A, et al. J Antimicrob Chemother. 1997 Jul;40(1):105-8. doi: 10.1093/jac/40.1.105. J Antimicrob Chemother. 1997. PMID: 9249211
Rapid type-specific diagnosis of adenovirus type 4 infection using a hexon-based quantitative fluorogenic PCR.
Houng HS, Liang S, Chen CM, Keith J, Echavarria M, Sanchez JL, Kolavic SA, Vaughn DW, Binn LN. Houng HS, et al. Diagn Microbiol Infect Dis. 2002 Apr;42(4):227-36. doi: 10.1016/s0732-8893(02)00356-5. Diagn Microbiol Infect Dis. 2002. PMID: 12007439
A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.
Blevitt JM, Hack MD, Herman K, Chang L, Keith JM, Mirzadegan T, Rao NL, Lebsack AD, Milla ME. Blevitt JM, et al. J Biol Chem. 2016 Jun 10;291(24):12724-31. doi: 10.1074/jbc.M116.725325. Epub 2016 Apr 16. J Biol Chem. 2016. PMID: 27129215 Free PMC article.
Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform.
Song J, Liu X, Zhu J, Tootoonchi M, Keith JM, Meduna SP, Dvorak CA, Eccles W, Krawczuk PJ, Blevitt JM, Wu J, Rao NL, Lebsack AD, Milla ME. Song J, et al. J Biomol Screen. 2016 Feb;21(2):127-35. doi: 10.1177/1087057115607815. Epub 2015 Oct 6. J Biomol Screen. 2016. PMID: 26442913
Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.
Keith JM, Gomez LA, Wolin RL, Barbier AJ, Wilson SJ, Boggs JD, Mazur C, Fraser IC, Lord B, Aluisio L, Lovenberg TW, Carruthers NI. Keith JM, et al. Bioorg Med Chem Lett. 2007 May 1;17(9):2603-7. doi: 10.1016/j.bmcl.2007.01.106. Epub 2007 Feb 4. Bioorg Med Chem Lett. 2007. PMID: 17317177
Heteroaryl urea inhibitors of fatty acid amide hydrolase: structure-mutagenicity relationships for arylamine metabolites.
Tichenor MS, Keith JM, Jones WM, Pierce JM, Merit J, Hawryluk N, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Wilson SJ, Wennerholm ML, Woestenborghs F, Beerens D, Luo L, Brown SM, Boeck MD, Chaplan SR, Breitenbucher JG. Tichenor MS, et al. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7357-62. doi: 10.1016/j.bmcl.2012.10.076. Epub 2012 Oct 22. Bioorg Med Chem Lett. 2012. PMID: 23141911
The SAR of brain penetration for a series of heteroaryl urea FAAH inhibitors.
Keith JM, Tichenor MS, Apodaca RL, Xiao W, Jones WM, Seierstad M, Pierce JM, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Wennerholm ML, Rizzolio M, Rynberg R, Chaplan SR, Breitenbucher JG. Keith JM, et al. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3109-3114. doi: 10.1016/j.bmcl.2016.05.001. Epub 2016 May 5. Bioorg Med Chem Lett. 2016. PMID: 27189675
Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate.
Keith JM, Apodaca R, Tichenor M, Xiao W, Jones W, Pierce J, Seierstad M, Palmer J, Webb M, Karbarz M, Scott B, Wilson S, Luo L, Wennerholm M, Chang L, Brown S, Rizzolio M, Rynberg R, Chaplan S, Breitenbucher JG. Keith JM, et al. ACS Med Chem Lett. 2012 Aug 22;3(10):823-7. doi: 10.1021/ml300186g. eCollection 2012 Oct 11. ACS Med Chem Lett. 2012. PMID: 24900385 Free PMC article.
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