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De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability.
McCarthy SE, Gillis J, Kramer M, Lihm J, Yoon S, Berstein Y, Mistry M, Pavlidis P, Solomon R, Ghiban E, Antoniou E, Kelleher E, O'Brien C, Donohoe G, Gill M, Morris DW, McCombie WR, Corvin A. McCarthy SE, et al. Among authors: kelleher e. Mol Psychiatry. 2014 Jun;19(6):652-8. doi: 10.1038/mp.2014.29. Epub 2014 Apr 29. Mol Psychiatry. 2014. PMID: 24776741 Free PMC article.
The shock of the new: progress in schizophrenia genomics.
Moore S, Kelleher E, Corvin A. Moore S, et al. Among authors: kelleher e. Curr Genomics. 2011 Nov;12(7):516-24. doi: 10.2174/138920211797904089. Curr Genomics. 2011. PMID: 22547958 Free PMC article.
Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.
Irish Schizophrenia Genomics Consortium and the Wellcome Trust Case Control Consortium 2. Irish Schizophrenia Genomics Consortium and the Wellcome Trust Case Control Consortium 2. Biol Psychiatry. 2012 Oct 15;72(8):620-8. doi: 10.1016/j.biopsych.2012.05.035. Epub 2012 Aug 9. Biol Psychiatry. 2012. PMID: 22883433 Free PMC article.
An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.
Morris DW, Pearson RD, Cormican P, Kenny EM, O'Dushlaine CT, Perreault LP, Giannoulatou E, Tropea D, Maher BS, Wormley B, Kelleher E, Fahey C, Molinos I, Bellini S, Pirinen M, Strange A, Freeman C, Thiselton DL, Elves RL, Regan R, Ennis S, Dinan TG, McDonald C, Murphy KC, O'Callaghan E, Waddington JL, Walsh D, O'Donovan M, Grozeva D, Craddock N, Stone J, Scolnick E, Purcell S, Sklar P, Coe B, Eichler EE, Ophoff R, Buizer J, Szatkiewicz J, Hultman C, Sullivan P, Gurling H, Mcquillin A, St Clair D, Rees E, Kirov G, Walters J, Blackwood D, Johnstone M, Donohoe G; International Schizophrenia Consortium, SGENE+ Consortium; O'Neill FA; Wellcome Trust Case Control Consortium 2; Kendler KS, Gill M, Riley BP, Spencer CC, Corvin A. Morris DW, et al. Among authors: kelleher e. Hum Mol Genet. 2014 Jun 15;23(12):3316-26. doi: 10.1093/hmg/ddu025. Epub 2014 Jan 28. Hum Mol Genet. 2014. PMID: 24474471 Free PMC article.
The phenotypic manifestations of rare CNVs in schizophrenia.
Merikangas AK, Segurado R, Cormican P, Heron EA, Anney RJ, Moore S, Kelleher E, Hargreaves A, Anderson-Schmidt H, Gill M, Gallagher L, Corvin A. Merikangas AK, et al. Among authors: kelleher e. Schizophr Res. 2014 Sep;158(1-3):255-60. doi: 10.1016/j.schres.2014.06.016. Epub 2014 Jul 4. Schizophr Res. 2014. PMID: 24999052
Parental age, birth order and neurodevelopmental disorders.
Merikangas AK, Segurado R, Kelleher E, Hogan D, Delaney C, Gill M, Gallagher L, Corvin AP, Heron EA. Merikangas AK, et al. Among authors: kelleher e. Mol Psychiatry. 2016 Jun;21(6):728-30. doi: 10.1038/mp.2015.127. Epub 2015 Aug 25. Mol Psychiatry. 2016. PMID: 26303659 No abstract available.
Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis.
Rees E, Carrera N, Morgan J, Hambridge K, Escott-Price V, Pocklington AJ, Richards AL, Pardiñas AF; GROUP Investigators; McDonald C, Donohoe G, Morris DW, Kenny E, Kelleher E, Gill M, Corvin A, Kirov G, Walters JTR, Holmans P, Owen MJ, O'Donovan MC. Rees E, et al. Among authors: kelleher e. Biol Psychiatry. 2019 Apr 1;85(7):554-562. doi: 10.1016/j.biopsych.2018.08.022. Epub 2018 Oct 1. Biol Psychiatry. 2019. PMID: 30420267 Free PMC article.
Autoantibodies and Psychosis.
Kelleher E, Barry H, Cotter DR, Corvin A, Murphy KC. Kelleher E, et al. Curr Top Behav Neurosci. 2020;44:85-123. doi: 10.1007/7854_2019_90. Curr Top Behav Neurosci. 2020. PMID: 31292938 Review.
129 results