Keller SN - Search Results

1

Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase.

Maines LW, Fitzpatrick LR, French KJ, Zhuang Y, Xia Z, Keller SN, Upson JJ, Smith CD. Maines LW, et al. Among authors: keller sn. Dig Dis Sci. 2008 Apr;53(4):997-1012. doi: 10.1007/s10620-007-0133-6. Epub 2007 Dec 4. Dig Dis Sci. 2008. PMID: 18058233 Free PMC article.

2

Antitumor activity of sphingosine kinase inhibitors.

French KJ, Upson JJ, Keller SN, Zhuang Y, Yun JK, Smith CD. French KJ, et al. Among authors: keller sn. J Pharmacol Exp Ther. 2006 Aug;318(2):596-603. doi: 10.1124/jpet.106.101345. Epub 2006 Apr 21. J Pharmacol Exp Ther. 2006. PMID: 16632640

3

Discovery and characterization of inhibitors of human palmitoyl acyltransferases.

Ducker CE, Griffel LK, Smith RA, Keller SN, Zhuang Y, Xia Z, Diller JD, Smith CD. Ducker CE, et al. Among authors: keller sn. Mol Cancer Ther. 2006 Jul;5(7):1647-59. doi: 10.1158/1535-7163.MCT-06-0114. Mol Cancer Ther. 2006. PMID: 16891450 Free PMC article.

4

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2.

French KJ, Zhuang Y, Maines LW, Gao P, Wang W, Beljanski V, Upson JJ, Green CL, Keller SN, Smith CD. French KJ, et al. Among authors: keller sn. J Pharmacol Exp Ther. 2010 Apr;333(1):129-39. doi: 10.1124/jpet.109.163444. Epub 2010 Jan 8. J Pharmacol Exp Ther. 2010. PMID: 20061445 Free PMC article.

5

2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance.

Gangjee A, Namjoshi OA, Keller SN, Smith CD. Gangjee A, et al. Among authors: keller sn. Bioorg Med Chem. 2011 Jul 15;19(14):4355-65. doi: 10.1016/j.bmc.2011.05.030. Epub 2011 May 23. Bioorg Med Chem. 2011. PMID: 21680190 Free PMC article.

6

Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.

Schrecengost RS, Keller SN, Schiewer MJ, Knudsen KE, Smith CD. Schrecengost RS, et al. Among authors: keller sn. Mol Cancer Res. 2015 Dec;13(12):1591-601. doi: 10.1158/1541-7786.MCR-14-0626. Epub 2015 Aug 13. Mol Cancer Res. 2015. PMID: 26271487 Free PMC article.

7

In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183.

Schrecengost RS, Green CL, Zhuang Y, Keller SN, Smith RA, Maines LW, Smith CD. Schrecengost RS, et al. Among authors: keller sn. J Pharmacol Exp Ther. 2018 Apr;365(1):107-116. doi: 10.1124/jpet.117.245738. Epub 2018 Feb 6. J Pharmacol Exp Ther. 2018. PMID: 29434052 Free PMC article.

8

Recent Progress in the Development of Opaganib for the Treatment of Covid-19.

Smith CD, Maines LW, Keller SN, Katz Ben-Yair V, Fathi R, Plasse TF, Levitt ML. Smith CD, et al. Among authors: keller sn. Drug Des Devel Ther. 2022 Jul 12;16:2199-2211. doi: 10.2147/DDDT.S367612. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35855741 Free PMC article. Review.

9

Opaganib Protects against Radiation Toxicity: Implications for Homeland Security and Antitumor Radiotherapy.

Maines LW, Schrecengost RS, Zhuang Y, Keller SN, Smith RA, Green CL, Smith CD. Maines LW, et al. Among authors: keller sn. Int J Mol Sci. 2022 Oct 29;23(21):13191. doi: 10.3390/ijms232113191. Int J Mol Sci. 2022. PMID: 36361977 Free PMC article.

10

The Sphingosine Kinase 2 Inhibitor Opaganib Protects Against Acute Kidney Injury in Mice.

Maines LW, Green CL, Keller SN, Fitzpatrick LR, Smith CD. Maines LW, et al. Among authors: keller sn. Int J Nephrol Renovasc Dis. 2022 Nov 17;15:323-334. doi: 10.2147/IJNRD.S386396. eCollection 2022. Int J Nephrol Renovasc Dis. 2022. PMID: 36420520 Free PMC article.

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