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The Notch1/c-Myc pathway in T cell leukemia.
Sharma VM, Draheim KM, Kelliher MA. Sharma VM, et al. Cell Cycle. 2007 Apr 15;6(8):927-30. doi: 10.4161/cc.6.8.4134. Epub 2007 Apr 11. Cell Cycle. 2007. PMID: 17404512
NF-kappaB activation in premalignant mouse tal-1/scl thymocytes and tumors.
O'Neil J, Ventura JJ, Cusson N, Kelliher M. O'Neil J, et al. Blood. 2003 Oct 1;102(7):2593-6. doi: 10.1182/blood-2003-01-0090. Epub 2003 Jun 19. Blood. 2003. PMID: 12816868
The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase.
Lee TH, Huang Q, Oikemus S, Shank J, Ventura JJ, Cusson N, Vaillancourt RR, Su B, Davis RJ, Kelliher MA. Lee TH, et al. Mol Cell Biol. 2003 Nov;23(22):8377-85. doi: 10.1128/mcb.23.22.8377-8385.2003. Mol Cell Biol. 2003. PMID: 14585994 Free PMC article.
TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.
O'Neil J, Shank J, Cusson N, Murre C, Kelliher M. O'Neil J, et al. Cancer Cell. 2004 Jun;5(6):587-96. doi: 10.1016/j.ccr.2004.05.023. Cancer Cell. 2004. PMID: 15193261
Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
Cusson-Hermance N, Khurana S, Lee TH, Fitzgerald KA, Kelliher MA. Cusson-Hermance N, et al. J Biol Chem. 2005 Nov 4;280(44):36560-6. doi: 10.1074/jbc.M506831200. Epub 2005 Aug 22. J Biol Chem. 2005. PMID: 16115877
Activating Notch1 mutations in mouse models of T-ALL.
O'Neil J, Calvo J, McKenna K, Krishnamoorthy V, Aster JC, Bassing CH, Alt FW, Kelliher M, Look AT. O'Neil J, et al. Blood. 2006 Jan 15;107(2):781-5. doi: 10.1182/blood-2005-06-2553. Epub 2005 Sep 15. Blood. 2006. PMID: 16166587 Free PMC article.
p16Ink4a or p19Arf loss contributes to Tal1-induced leukemogenesis in mice.
Shank-Calvo JA, Draheim K, Bhasin M, Kelliher MA. Shank-Calvo JA, et al. Oncogene. 2006 May 18;25(21):3023-31. doi: 10.1038/sj.onc.1209326. Oncogene. 2006. PMID: 16407836
Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
Sharma VM, Calvo JA, Draheim KM, Cunningham LA, Hermance N, Beverly L, Krishnamoorthy V, Bhasin M, Capobianco AJ, Kelliher MA. Sharma VM, et al. Mol Cell Biol. 2006 Nov;26(21):8022-31. doi: 10.1128/MCB.01091-06. Epub 2006 Sep 5. Mol Cell Biol. 2006. PMID: 16954387 Free PMC article.
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